根据人外周血淋巴细胞对不溶性组胺的亲和力进行分离。男性和女性之间的主要差异。

Segregation of human peripheral blood lymphocytes according to their affinity for insolubilized histamine. Principal differences between males and females.

作者信息

Tartakovsky B, Segal S, Shani A, Hellerstein S, Weinstein Y, Bentwich Z

出版信息

Clin Exp Immunol. 1979 Oct;38(1):166-74.

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1537841/

Abstract

An attempt was made to investigate the possible existence of differences in the composition of peripheral blood lymphocytes between males and females. Using affinity chromatography of human peripheral mononuclear cells on insolubilized histamine together with staining by fluoresceinated histamine-rabbit serum albumin (HRSA) we revealed that males possess a significantly higher proportion of mononuclear cells which bind to HRSA. These results are also reflected in sex-related differences in proliferative responses of the HRSA-non-adherent mononuclear cell population to T cell-dependent mitogens antigens and allogeneic mononuclear cells.

摘要

研究人员试图调查男性和女性外周血淋巴细胞组成是否可能存在差异。通过将人外周血单个核细胞在固定化组胺上进行亲和层析，并结合荧光素化组胺-兔血清白蛋白（HRSA）染色，我们发现男性中与HRSA结合的单个核细胞比例显著更高。这些结果也反映在HRSA非黏附单个核细胞群体对T细胞依赖性丝裂原抗原和同种异体单个核细胞增殖反应的性别相关差异上。

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