Geisler M W, Polich J
Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037.
Psychophysiology. 1992 Jan;29(1):86-94. doi: 10.1111/j.1469-8986.1992.tb02019.x.
To determine how individual differences stemming from activity preference, previous food intake, and time-of-day affect the P300 or P3 event-related brain potential (ERP), subject groups who varied orthogonally on these factors were compared using a simple auditory discrimination task to elicit the ERPs. Amplitude of the P3 component for morning-preferring subjects who had eaten recently was relatively large for both the morning and evening measurement time groups. P3 amplitude for the morning-preferring subjects who had not eaten recently was large for those measured in the morning and relatively small for those subjects measured in the evening. For evening-preferring subjects who had eaten recently, P3 amplitude was again relatively large for both the morning and evening measurement time groups. Evening-preferring subjects who had not eaten recently produced very small P3 components for those measured in the morning compared to the large components produced by those subjects measured in the evening. P3 latency tended to be longer for all subjects who had not eaten recently compared to those who had. The results suggest that the P3 component is sensitive to physiological and psychological changes originating from individual differences related to bodily state, which perhaps stems from individual differences in arousal level.
为了确定由活动偏好、先前食物摄入量和一天中的时间所导致的个体差异如何影响P300或P3事件相关脑电位（ERP），使用简单听觉辨别任务诱发ERP，对在这些因素上呈正交变化的受试者组进行了比较。对于近期进食的晨型受试者，无论是在上午还是晚上测量时间组，P3成分的波幅都相对较大。对于近期未进食的晨型受试者，上午测量的受试者P3波幅较大，而晚上测量的受试者P3波幅相对较小。对于近期进食的夜型受试者，上午和晚上测量时间组的P3波幅再次相对较大。与晚上测量的受试者产生的大波幅相比，近期未进食的夜型受试者在上午测量时产生的P3成分非常小。与进食的受试者相比，所有近期未进食的受试者的P3潜伏期往往更长。结果表明，P3成分对源于与身体状态相关的个体差异的生理和心理变化敏感，这可能源于唤醒水平的个体差异。
