Geisler M W, Polich J
Department of Neuropharmacology, Research Institute of Scripps Clinic, La Jolla, CA 92037.
Biol Psychol. 1990 Oct;31(2):117-36. doi: 10.1016/0301-0511(90)90012-l.
The P300 or P3 component of the event-related brain potential (ERP) was obtained from five groups of 24 young adult subjects, with each group measured at a different time of day (8 a.m., 11 a.m., 2 p.m., 5 p.m., 8 p.m.). An activity-preference questionnaire was used to ensure that an equitable number of morning- and evening-preferring subjects were obtained for each testing time. P3 measures, physiological (body temperature, heart rate, subjective alertness), and cognitive performance (digit span, prose memory, digit symbol) variables were assessed. P3 amplitude and latency were not affected directly by the time of day. However, P3 amplitude was smaller in subjects who had not eaten within 6 hours of testing relative to subjects who had a recent meal, and P3 latency was correlated negatively with body temperature. The findings suggest that although the P3 ERP is not influenced by circadian rhythms, it is related to recency of food intake and physiological factors which change with time of day.
事件相关脑电位（ERP）的P300或P3成分取自五组，每组24名年轻成年受试者，每组在一天中的不同时间（上午8点、上午11点、下午2点、下午5点、晚上8点）进行测量。使用一份活动偏好问卷，以确保在每个测试时间获得数量相当的偏好早晨和偏好晚上的受试者。评估了P3测量值、生理指标（体温、心率、主观警觉性）和认知表现（数字广度、散文记忆、数字符号）变量。P3波幅和潜伏期不受一天中时间的直接影响。然而，相对于最近进食的受试者，在测试前6小时内未进食的受试者的P3波幅较小，且P3潜伏期与体温呈负相关。研究结果表明，虽然P3 ERP不受昼夜节律影响，但它与食物摄入的近期情况以及随一天中时间变化的生理因素有关。
