饮食中钠对支气管哮喘严重程度的影响。
Effect of dietary sodium on the severity of bronchial asthma.
作者信息
Lieberman D, Heimer D
机构信息
Pulmonary Unit, Soroka Medical Center, Ben Gurion University Faculty of Health Sciences, Beer-Sheva, Israel.
出版信息
Thorax. 1992 May;47(5):360-2. doi: 10.1136/thx.47.5.360.
BACKGROUND
A high sodium intake has been found to increase bronchial reactivity in men with asthma. The effects of change in sodium intake on peak flow rate have not been determined.
METHODS
The effect of changing dietary salt intake for two weeks on the severity of asthma as measured by peak expiratory flow (PEF) was studied in 17 patients with mild asthma in an open randomised crossover trial. PEF measurements were made by the patients in their own homes. Patients were placed on three levels of dietary sodium intake: normal, low, and high. Sodium intake was assessed by 24 hour urine collection.
RESULTS
The mean (SD) urine sodium was 147 (45), 84 (32), and 201 (73) mmol/24 hours in the normal, low, and high sodium intake periods respectively. There were no significant differences in PEF or PEF amplitude (highest--lowest PEF), an index of asthma lability, between the three dietary salt periods. CONCLUSION A low and high dietary salt intake for two weeks has no effect on peak expiratory flow in patients with mild asthma.
背景
研究发现高钠摄入会增加哮喘男性患者的支气管反应性。钠摄入量变化对峰值流速的影响尚未确定。
方法
在一项开放随机交叉试验中，对17例轻度哮喘患者研究了为期两周改变饮食盐摄入量对哮喘严重程度（通过呼气峰值流速（PEF）衡量）的影响。PEF测量由患者在自己家中进行。患者被安排在三种饮食钠摄入水平：正常、低和高。通过收集24小时尿液评估钠摄入量。
结果
正常、低和高钠摄入期的平均（标准差）尿钠分别为147（45）、84（32）和201（73）mmol/24小时。在三个饮食盐摄入期之间，PEF或PEF幅度（最高 - 最低PEF）（哮喘不稳定指数）无显著差异。结论：两周的低和高饮食盐摄入对轻度哮喘患者的呼气峰值流速无影响。
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