Burney P G, Britton J R, Chinn S, Tattersfield A E, Platt H S, Papacosta A O, Kelson M C
Br Med J (Clin Res Ed). 1986 Jun 7;292(6534):1483-6. doi: 10.1136/bmj.292.6534.1483.
A relation between the prevalence of asthma and economic development has been suggested by studies in migrants and other surveys in developing countries. That this correlation might be partially explained by an increased intake of salt in the diet is supported by the observation that sales of table salt in the different regions of England and Wales are independently correlated with mortality from asthma for men and for children. As part of a wider survey of asthma 138 men living in two Hampshire villages and aged 18-64 were given a bronchial histamine challenge test and had their 24 hour urinary excretion of sodium measured. Bronchial reactivity was strongly related to 24 hour excretion of sodium after allowing for the effects of age, atopy, and cigarette smoking, there being on average a 10-fold difference in reactivity over the 95% range of sodium excretion recorded in the study. The data suggest that a high sodium diet may potentiate bronchial reactivity.
移民研究以及发展中国家的其他调查表明，哮喘患病率与经济发展之间存在某种关联。英格兰和威尔士不同地区的食盐销售量与男性和儿童的哮喘死亡率独立相关，这一观察结果支持了以下观点：这种相关性可能部分归因于饮食中盐分摄入量的增加。作为一项更广泛的哮喘调查的一部分，对居住在汉普郡两个村庄、年龄在18至64岁之间的138名男性进行了支气管组胺激发试验，并测量了他们24小时的尿钠排泄量。在考虑年龄、特应性和吸烟的影响后，支气管反应性与24小时尿钠排泄量密切相关，在该研究记录的95%的钠排泄范围内，反应性平均相差10倍。数据表明，高盐饮食可能会增强支气管反应性。
