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决策的神经生物学:从神经认知和临床角度的选择性综述

Neurobiology of decision making: a selective review from a neurocognitive and clinical perspective.

作者信息

Ernst Monique, Paulus Martin P

机构信息

Section of Developmental and Affective Neuroscience, National Institute of Mental Health, National Institutes of Health, 15K North Drive, Bethesda, MD 20892, USA.

出版信息

Biol Psychiatry. 2005 Oct 15;58(8):597-604. doi: 10.1016/j.biopsych.2005.06.004. Epub 2005 Aug 10.

Abstract

We present a temporal map of key processes that occur during decision making, which consists of three stages: 1) formation of preferences among options, 2) selection and execution of an action, and 3) experience or evaluation of an outcome. This framework can be used to integrate findings of traditional choice psychology, neuropsychology, brain lesion studies, and functional neuroimaging. Decision making is distributed across various brain centers, which are differentially active across these stages of decision making. This approach can be used to follow developmental trajectories of the different stages of decision making and to identify unique deficits associated with distinct psychiatric disorders.

摘要

我们展示了决策过程中关键进程的时间图谱,该图谱由三个阶段组成:1)在选项中形成偏好;2)选择并执行一个行动;3)体验或评估一个结果。这个框架可用于整合传统选择心理学、神经心理学、脑损伤研究和功能性神经成像的研究结果。决策过程分布于不同的脑区中心,这些脑区在决策的不同阶段有不同程度的激活。这种方法可用于追踪决策不同阶段的发展轨迹,并识别与不同精神疾病相关的独特缺陷。

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