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生物可膨胀假体:儿童恶性骨肿瘤切除术后的新视角。

The bioexpandable prosthesis: a new perspective after resection of malignant bone tumors in children.

作者信息

Baumgart Rainer, Hinterwimmer Stefan, Krammer Michael, Muensterer Oliver, Mutschler Wolf

机构信息

Klinikum der Universität München Chirurgische Klinik und Poliklinik-Innenstadt, Munich, Germany.

出版信息

J Pediatr Hematol Oncol. 2005 Aug;27(8):452-5. doi: 10.1097/01.mph.0000178268.07830.d5.

Abstract

Bone reconstruction after resection of malignant bone tumors of the lower extremity in children and adolescents remains a challenge in limb-sparing surgery. Equal limb length at maturity and good functional outcome are the main goals of these surgeries but often are difficult to achieve. Expandable endoprostheses are available but usually require repeated operative interventions for lengthening. Moreover, as the size of the implant increases, the proportion of the implant relative to the remaining bone increases, generating a biomechanical disadvantage to the limb. The authors describe a new concept combining an endoprosthesis with a fully implantable motorized distraction nail that can be activated in gradual steps to lengthen the remaining bone by callus distraction. New high-quality bone is growing and the proportion of prosthesis length compared with leg length develops in favor of the remaining bone.

摘要

儿童和青少年下肢恶性骨肿瘤切除术后的骨重建仍是保肢手术中的一项挑战。实现成熟时肢体等长和良好的功能结果是这些手术的主要目标,但往往难以达成。可扩张假体虽已可用,但通常需要多次手术干预来延长肢体。此外,随着植入物尺寸增大,植入物相对于剩余骨骼的比例增加,给肢体带来生物力学上的劣势。作者描述了一种将假体与完全可植入的电动撑开钉相结合的新概念,该撑开钉可逐步激活,通过骨痂撑开延长剩余骨骼。新的优质骨在生长,假体长度与腿长的比例朝着有利于剩余骨骼的方向发展。

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