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骨骼未成熟患者的肢体挽救

Limb salvage in the skeletally immature patient.

作者信息

Lewis Valerae O

机构信息

University of Texas M.D. Anderson Cancer Center, Houston, TX 77230, USA.

出版信息

Curr Oncol Rep. 2005 Jul;7(4):285-92. doi: 10.1007/s11912-005-0052-7.

Abstract

The most common tumors of bone, osteosarcoma and Ewing sarcoma, commonly occur in the skeletally immature patient. Historically, amputation was the procedure of choice; however, improved oncologic outcome and technical advances in limb salvage surgery have made limb salvage therapy a feasible and valuable treatment option. Nevertheless, depending on the extent of the lesion within the long bone, it may be difficult to spare the physis, and hence, in the skeletally immature patient, resection of a sarcoma of bone can create a limb-length discrepancy and gait abnormalities. This article reviews the limb salvage options available for the skeletally immature patient who requires reconstruction of a segmental long bone defect.

摘要

最常见的骨肿瘤,骨肉瘤和尤因肉瘤,通常发生在骨骼未成熟的患者中。从历史上看,截肢是首选的手术方式;然而,肿瘤治疗效果的改善以及保肢手术技术的进步,使得保肢治疗成为一种可行且有价值的治疗选择。尽管如此,根据长骨内病变的范围,可能难以保留骨骺,因此,对于骨骼未成熟的患者,骨肉瘤的切除可能会导致肢体长度差异和步态异常。本文综述了对于需要重建节段性长骨缺损的骨骼未成熟患者可用的保肢选择。

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