醋酸三丁基锡对一些常见山药腐烂真菌的抗真菌活性。
Antifungal activity of n-tributyltin acetate against some common yam rot fungi.
作者信息
Olurinola P F, Ehinmidu J O, Bonire J J
机构信息
Department of Pharmaceutics and Pharmaceutical Microbiology, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria, Nigeria.
出版信息
Appl Environ Microbiol. 1992 Feb;58(2):758-60. doi: 10.1128/aem.58.2.758-760.1992.
The antifungal activity of n-tributyltin acetate (TBTA) was examined in relation to combating yam rot disease. TBTA exhibited a significant effect in vitro and in vivo on four yam rot fungal isolates tested. However, the in vitro toxicity of TBTA was drastically reduced when 2.5% Tween 80 was the solvent instead of 25% acetone, as indicated by the MICs of 156.0 and 5.0 micrograms/ml, respectively.
研究了醋酸三丁基锡（TBTA）针对防治山药腐烂病的抗真菌活性。TBTA在体外和体内对四种受试的山药腐烂真菌分离株均表现出显著效果。然而，当以2.5%吐温80作为溶剂而非25%丙酮时，TBTA的体外毒性大幅降低，其最低抑菌浓度（MIC）分别为156.0微克/毫升和5.0微克/毫升。
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