Moloney Edward D, Egan Jim J, Kelly Peter, Wood Alfred E, Cooper Leslie T
Department of Respiratory Medicine, Mater Misericordiae University Hospital, Dublin, Ireland.
J Heart Lung Transplant. 2005 Aug;24(8):1103-10. doi: 10.1016/j.healun.2004.06.015.
Myocarditis is a major cause of end-stage heart failure and is responsible for up to 10% of cases of idiopathic dilated cardiomyopathy (IDC). Worldwide, approximately 45% of all heart transplants are performed for IDC and up to 8% for myocarditis. Early reports suggested that survival after transplantation for myocarditis was poor and patients had an increased risk of rejection. More recently, larger case series suggest that overall survival after transplantation for myocarditis is similar to survival after transplantation for other causes. However, certain disorders, including cardiac sarcoidosis and giant cell myocarditis (GCM), require heightened surveillance for post-transplantation disease recurrence. We present the case of a 42-year-old man with recurrence of GCM 8 years after transplantation and review the literature on the role of cardiac transplantation for patients with myocarditis.
心肌炎是终末期心力衰竭的主要病因，在特发性扩张型心肌病（IDC）病例中占比高达10%。在全球范围内，所有心脏移植手术中约45%是针对IDC进行的，而针对心肌炎的高达8%。早期报告显示，心肌炎患者移植后的生存率较低，且排斥反应风险增加。最近，更大规模的病例系列研究表明，心肌炎患者移植后的总体生存率与其他病因移植后的生存率相似。然而，某些疾病，包括心脏结节病和巨细胞心肌炎（GCM），需要加强对移植后疾病复发的监测。我们报告一例42岁男性在移植8年后出现GCM复发的病例，并回顾关于心肌炎患者心脏移植作用的文献。
