Jeste Dilip V, Blazer Dan G, First Michael
Department of Psychiatry, University of California, San Diego, California 92161, USA.
Biol Psychiatry. 2005 Aug 15;58(4):265-71. doi: 10.1016/j.biopsych.2005.02.004.
It is commonly thought and taught that most psychiatric disorders other than dementia are much less prevalent among the elderly than among younger adults. This perception is based on a relatively small number of published epidemiologic investigations of the incidence and prevalence of mental illnesses in elderly populations. Most of these studies have had a number of methodologic problems, including improper definitions and diagnostic criteria for older persons. A likely consequence of these misconceptions is that clinically significant and potentially treatable mental illnesses might be overlooked, misdiagnosed, and mistreated in elderly patients. Studies in community samples suggest that many older adults who experience clinically significant psychopathology do not fit easily into our existing nomenclature, and yet are disabled. There is a need to develop aging-appropriate diagnostic criteria for major psychiatric disorders. In this article, we discuss the potential causes of this diagnostic confusion. Four specific classes of disorders-mood (specifically depressive) disorders, schizophrenia (and related psychotic disorders), anxiety disorders, and substance use disorders-are discussed as examples. Finally, we suggest some future steps for clarifying this diagnostic confusion.
人们普遍认为并传授,除痴呆症外,大多数精神疾病在老年人中的患病率远低于年轻人。这种认知基于相对较少的已发表的关于老年人群体精神疾病发病率和患病率的流行病学调查。这些研究大多存在一些方法学问题,包括对老年人的定义和诊断标准不当。这些误解可能导致的一个后果是,临床上显著且可能可治疗的精神疾病在老年患者中可能被忽视、误诊和误治。社区样本研究表明,许多经历临床上显著精神病理学症状的老年人不容易归入我们现有的命名体系,但他们却有功能障碍。需要为主要精神疾病制定适合老年人的诊断标准。在本文中,我们讨论这种诊断困惑的潜在原因。作为例子,我们讨论了四类特定的疾病——情绪(特别是抑郁)障碍、精神分裂症(及相关精神病性障碍)、焦虑障碍和物质使用障碍。最后,我们提出了一些未来澄清这种诊断困惑的步骤。