• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

对乙酰氨基酚在活性炭上的体外吸附

In vitro adsortpion of acetaminophen onto activated charcoal.

作者信息

Bainbridge C A, Kelly E L, Walking W D

出版信息

J Pharm Sci. 1977 Apr;66(4):480-3. doi: 10.1002/jps.2600660405.

DOI:10.1002/jps.2600660405
PMID:16111
Abstract

In vitro experiments supported in vivo evidence that activated charcoal is effective in adsorbing acetaminophen. In the physiologic pH range, adsorption was rapid and pH independent. Adsorption, however, was dependent upon the quantity of activated charcoal employed, becoming more complete as the quantity of activated charcoal was increased.

摘要

体外实验支持了体内证据,即活性炭能有效吸附对乙酰氨基酚。在生理pH范围内,吸附迅速且与pH无关。然而,吸附取决于所用活性炭的量,随着活性炭量的增加,吸附变得更完全。

相似文献

1
In vitro adsortpion of acetaminophen onto activated charcoal.对乙酰氨基酚在活性炭上的体外吸附
J Pharm Sci. 1977 Apr;66(4):480-3. doi: 10.1002/jps.2600660405.
2
In vitro coadsorption of acetaminophen and N-acetylcysteine onto activated carbon powder.对乙酰氨基酚和N-乙酰半胱氨酸在活性炭粉末上的体外共吸附作用
J Pharm Sci. 1986 Sep;75(9):904-6. doi: 10.1002/jps.2600750918.
3
Effect of ethanol and pH on the adsorption of acetaminophen (paracetamol) to high surface activated charcoal, in vitro studies.乙醇和pH值对乙酰氨基酚(扑热息痛)吸附到高比表面积活性炭上的影响:体外研究
J Toxicol Clin Toxicol. 2002;40(1):59-67. doi: 10.1081/clt-120002886.
4
Inhibitory effect of sorbitol on acetaminophen adsorption by activated carbon.山梨醇对活性炭吸附对乙酰氨基酚的抑制作用。
J Environ Sci Health A Tox Hazard Subst Environ Eng. 2002;37(5):905-12. doi: 10.1081/ese-120003596.
5
In vitro adsorption of tilidine HCl by activated charcoal.活性炭对盐酸替利定的体外吸附作用。
J Toxicol Clin Toxicol. 1986;24(6):503-17. doi: 10.3109/15563658608995390.
6
In vitro study of the effect of dog food on the adsorptive capacity of activated charcoal.
J Vet Emerg Crit Care (San Antonio). 2013 May-Jun;23(3):263-7. doi: 10.1111/vec.12037. Epub 2013 Mar 20.
7
Effect of particle size on the adsorption of theophylline onto activated charcoal, in vitro study.粒径对茶碱在活性炭上吸附作用的体外研究
Chudoku Kenkyu. 2003 Jan;16(1):57-62.
8
The effect of food and ice cream on the adsorption capacity of paracetamol to high surface activated charcoal: in vitro studies.食物和冰淇淋对扑热息痛在高比表面积活性炭上吸附能力的影响:体外研究
Pharmacol Toxicol. 2003 Nov;93(5):233-7. doi: 10.1046/j.1600-0773.2003.pto930506.x.
9
In-vitro adsorption studies of isoniazid.
Hum Exp Toxicol. 1991 Mar;10(2):133-5. doi: 10.1177/096032719101000208.
10
The effect of ethanol and pH on the adsorption of drugs from simulated gastric fluid onto activated charcoal.乙醇和pH值对药物从模拟胃液中吸附到活性炭上的影响。
Ther Drug Monit. 2003 Jun;25(3):310-3. doi: 10.1097/00007691-200306000-00011.

引用本文的文献

1
Age-related pseudocapillarization of the liver sinusoidal endothelium impairs the hepatic clearance of acetaminophen in rats.年龄相关的肝窦内皮伪毛细血管化损害了大鼠对乙酰氨基酚的肝脏清除。
J Gerontol A Biol Sci Med Sci. 2011 Apr;66(4):400-8. doi: 10.1093/gerona/glq221. Epub 2011 Feb 7.
2
Clinical pharmacokinetics of oral activated charcoal in acute intoxications.口服活性炭在急性中毒中的临床药代动力学
Clin Pharmacokinet. 1982 Nov-Dec;7(6):465-89. doi: 10.2165/00003088-198207060-00001.
3
Oral activated charcoal in the treatment of intoxications. Role of single and repeated doses.
口服活性炭治疗中毒。单次和重复剂量的作用。
Med Toxicol Adverse Drug Exp. 1988 Jan-Dec;3(1):33-58. doi: 10.1007/BF03259930.
4
A ready-to-use activated charcoal mixture. Adsorption studies in vitro and in dogs: its influence on the intestinal secretion of theophylline in a rat model.一种即用型活性炭混合物。体外及犬体内吸附研究:其对大鼠模型中茶碱肠道分泌的影响。
Pharm Weekbl Sci. 1989 Apr 28;11(2):56-60. doi: 10.1007/BF01962976.
5
Comparative antidotal efficacy of activated charcoal tablets, capsules and suspension in healthy volunteers.
Eur J Clin Pharmacol. 1990;39(5):501-5. doi: 10.1007/BF00280944.
6
A comparison of the efficacy of gastric lavage, ipecacuanha and activated charcoal in the emergency management of paracetamol overdose.洗胃、吐根糖浆和活性炭在对乙酰氨基酚过量急救处理中的疗效比较。
Arch Emerg Med. 1990 Sep;7(3):148-54. doi: 10.1136/emj.7.3.148.