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印楝柠檬苦素对疟疾媒介斯氏按蚊(双翅目:蚊科)的影响。

Effects of neem limonoids on the malaria vector Anopheles stephensi Liston (Diptera: Culicidae).

作者信息

Nathan Sengottayan Senthil, Kalaivani Kandaswamy, Murugan Kadarkarai

机构信息

Department of Environmental Engineering, Chonbuk National University, Jeonju City, South Korea.

出版信息

Acta Trop. 2005 Oct;96(1):47-55. doi: 10.1016/j.actatropica.2005.07.002.

DOI:10.1016/j.actatropica.2005.07.002
PMID:16112073
Abstract

The effects of the neem (Azadirachta indica A. Juss) limonoids azadirachtin, salannin, deacetylgedunin, gedunin, 17-hydroxyazadiradione and deacetylnimbin on Anopheles stephensi Liston (Diptera: Culicidae) were investigated. In exploring advantages of pure neem limonoids, we studied the larvicidal, pupicidal, adulticidal and antiovipositional activity of neem limonoids. Azadirachtin, salannin and deacetylgedunin showed high bioactivity at all doses, while the rest of the neem limonoids were less active, and were only biologically active at high doses. Azadirachtin was the most potent in all experiments and produced almost 100% larval mortality at 1 ppm concentration. In general, first to third larval instars were more susceptible to the neem limonoids. Neem products may have benefits in mosquito control programs.

摘要

研究了印楝(Azadirachta indica A. Juss)柠檬苦素类化合物印楝素、萨兰宁、脱乙酰格杜宁、格杜宁、17-羟基印楝二酮和脱乙酰印楝宁对斯氏按蚊(双翅目:蚊科)的影响。在探索纯印楝柠檬苦素类化合物的优势时,我们研究了印楝柠檬苦素类化合物的杀幼虫、杀蛹、杀成虫和抗产卵活性。印楝素、萨兰宁和脱乙酰格杜宁在所有剂量下均表现出高生物活性,而其余印楝柠檬苦素类化合物活性较低,仅在高剂量时具有生物活性。印楝素在所有实验中效力最强,在1 ppm浓度下可导致近100%的幼虫死亡率。一般来说,一至三龄幼虫对印楝柠檬苦素类化合物更敏感。印楝产品可能在蚊虫控制项目中具有益处。

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