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韩国成年人习惯性打鼾与代谢综合征各组分的关系。

Relation of habitual snoring with components of metabolic syndrome in Korean adults.

作者信息

Cho Namhan, Joo SoonJae, Kim JinKwan, Abbott Robert D, Kim JeHyeong, Kimm Kuchan, Shin Chol

机构信息

Department of Preventive Medicine, Ajou University School of Medicine, Republic of Korea.

出版信息

Diabetes Res Clin Pract. 2006 Mar;71(3):256-63. doi: 10.1016/j.diabres.2005.06.011. Epub 2005 Aug 19.

DOI:10.1016/j.diabres.2005.06.011
PMID:16112240
Abstract

AIMS

To examine the association between habitual snoring and components of the metabolic syndrome in Korean adults. Whether these associations are independent of obesity was also explored.

METHODS

Four thousand five hundred and six men and 5041 women aged 40-69 years from the Korean Health and Genome Study were examined. Information of snoring frequency was obtained by a questionnaire and components of the metabolic syndrome were measured.

RESULTS

There was a clear dose-response relationship between the increasing frequency of snoring and the higher prevalence of each component of the metabolic syndrome (P<0.001). After adjustment for age, abdominal obesity, and the other metabolic components, hypertension was significantly associated with a 1.2-fold excess of habitual snoring in both men (P<0.05) and women (P<0.05). The association of habitual snoring with hypertension was unaltered by obesity. Regardless of the presence or absence of abdominal obesity, there was an increase in the prevalence of habitual snoring as the number of metabolic abnormalities increased.

CONCLUSIONS

Habitual snoring is associated with hypertension independent of obesity. While the relationship between habitual snoring and obesity is well recognized, characterization of the role of the other components of the metabolic syndrome as a cause or result of habitual snoring warrants a further study.

摘要

目的

研究韩国成年人习惯性打鼾与代谢综合征各组分之间的关联。同时探讨这些关联是否独立于肥胖。

方法

对来自韩国健康与基因组研究的4506名40 - 69岁男性和5041名40 - 69岁女性进行检查。通过问卷调查获取打鼾频率信息,并测量代谢综合征的各组分。

结果

打鼾频率增加与代谢综合征各组分较高的患病率之间存在明确的剂量反应关系(P<0.001)。在调整年龄、腹型肥胖和其他代谢组分后,高血压与男性(P<0.05)和女性(P<0.05)习惯性打鼾增加1.2倍显著相关。习惯性打鼾与高血压的关联不受肥胖影响。无论是否存在腹型肥胖,随着代谢异常数量的增加,习惯性打鼾的患病率均升高。

结论

习惯性打鼾与高血压相关,且独立于肥胖。虽然习惯性打鼾与肥胖之间的关系已得到充分认识,但代谢综合征其他组分作为习惯性打鼾的原因或结果的作用特征值得进一步研究。

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