Dolk H
Epidemiology and Health Services Research, University of Ulster at Jordanstown, Shore Rd, Newtownabbey BT37 OQB, UK.
Arch Dis Child Fetal Neonatal Ed. 2005 Sep;90(5):F355-8. doi: 10.1136/adc.2004.062810.
The surveillance of congenital anomalies serves two main purposes: to facilitate the identification of teratogenic (malformation causing) exposures and to assess the impact of primary prevention and prenatal screening policy and practice at a population level. EUROCAT, the European network of population based registers for the epidemiological surveillance of congenital anomalies, now covers 1.2 million births per year, a quarter of births in Europe. The added value of European collaboration is particularly great for congenital anomalies, coming from the opportunity to pool data, to compare data between regions and countries, to give a common response to European public health questions, and to share expertise and resources, including computing tools. EUROCAT provides essential epidemiological information on congenital anomalies in Europe, facilitates the early warning of teratogenic exposures, evaluates the effectiveness of primary prevention, assesses the impact of developments in prenatal screening, acts as an information and resource centre regarding clusters, provides a ready collaborative network and infrastructure for research, and acts as a catalyst for the setting up of registries throughout Europe.
便于识别致畸（导致畸形）暴露因素，并在人群层面评估一级预防及产前筛查政策与实践的影响。欧洲先天性异常流行病学监测基于人群登记的网络EUROCAT，目前每年涵盖120万例出生，占欧洲出生人口的四分之一。欧洲合作对于先天性异常的附加值尤为巨大，这源于汇集数据、比较不同地区和国家数据、共同回应欧洲公共卫生问题以及共享专业知识和资源（包括计算工具）的机会。EUROCAT提供有关欧洲先天性异常的基本流行病学信息，便于对致畸暴露因素进行早期预警，评估一级预防的效果，评估产前筛查进展的影响，充当有关聚集性病例的信息和资源中心，为研究提供现成的合作网络和基础设施，并推动在欧洲各地建立登记处。
