Monov Gabriel, Fuerst Gabor, Tepper Gabor, Watzak Georg, Zechner Werner, Watzek Georg
Department of Oral Surgery, University of Vienna School of Dentistry, Ludwig Boltzmann Institute of Oral Implantology, Vienna, Austria.
Clin Oral Implants Res. 2005 Aug;16(4):461-5. doi: 10.1111/j.1600-0501.2005.01157.x.
Using a one-stage surgical protocol, a total of 34 Brånemark Mk-III Ti-Unite implants with a length of 13 mm and a diameter of 3.75 mm were inserted in 10 edentulous mandibles. Of these, seven patients received four and three patients two interforaminal implants. All implants were followed with repeated stability measurements by means of resonance frequency analysis at different time interval: 0, 4, 8, 12, 16, 20, 24, 28, 32, 36, 40, 44 days. In quadrant III platelet-rich plasma (PRP) was instilled locally before implant placement, while no PRP was added in quadrant IV to serve as control group (split-mouth design). Results showed no statistically significant difference between the two groups. Nonetheless, both groups (PRP+control) showed a highly significant reduction of the implant stability quotient (P<0.001) between days 0 and 4. However, no difference was noted between the two groups after day 4, it may be concluded that the instillation of PRP during implant placement in the lower anterior mandible did not add additional benefit.
采用一期手术方案，将34枚长度为13 mm、直径为3.75 mm的Brånemark Mk-III Ti-Unite种植体植入10例无牙下颌骨。其中，7例患者植入4枚种植体，3例患者植入2枚种植体，均位于下颌孔间区域。所有种植体在不同时间间隔（0、4、8、12、16、20、24、28、32、36、40、44天）通过共振频率分析进行反复稳定性测量。在第三象限，种植体植入前局部注入富血小板血浆（PRP），而在第四象限不注入PRP作为对照组（分口设计）。结果显示两组之间无统计学显著差异。尽管如此，两组（PRP组+对照组）在第0天和第4天之间种植体稳定性商数均显著降低（P<0.001）。然而，在第4天之后两组之间未观察到差异，可以得出结论，在下颌前牙区种植体植入过程中注入PRP并未带来额外益处。
