Lokwani Bhavna Vasudev, Gupta Deeksha, Agrawal Reema Sarvesh, Mehta Sonal, Nirmal Narendra J
Department of Prosthodontics, Manubhai Patel Dental College, Vadodara, Gujarat, India.
Department of Public Health Dentistry, Manubhai Patel Dental College, Vadodara, Gujarat, India.
J Indian Prosthodont Soc. 2020 Jan-Mar;20(1):3-10. doi: 10.4103/jips.jips_375_19. Epub 2020 Jan 27.
In the era of evidence based dentistry, a well-documented consolidated data about improvements in dentistry is a necessity. Concentrated growth factor (CGF) is an emerging trend in periodontology and now in implant dentistry. Various studies have been published in the literature evaluating the effect of CGF on implant osseointegration, implant stability, survival rate, sinus augmentation, and peri-implant defects. However, no systematic review has yet been documented. The present systematic review, being first of its kind, aimed to evaluate the potential outcomes of employing CGF in implant treatment. A literature search was carried out in PubMed and Google scholar for articles published between 2001 and 2019, with various keywords such as "CGF," "dental implant," "bone regeneration," "CGF," and "osseointegration." The screening of studies was done according to PRISMA guidelines. A total of eleven studies were included in this review. Majority of the included studies pointed toward the beneficial effects of CGF in implant treatment. CGF was seen to promote osseointegration and enhance bone regeneration. Although more clinical studies are required to validate the potential merits of CGF in the long run, the preliminary results seem promising.
在循证牙科时代，一份关于牙科改善情况的记录完备的综合数据是必要的。浓缩生长因子（CGF）是牙周病学领域以及如今种植牙科领域的一种新兴趋势。文献中已发表了多项研究，评估CGF对种植体骨整合、种植体稳定性、存活率、上颌窦提升以及种植体周围缺损的影响。然而，尚未有系统性综述的记录。本系统性综述是同类中的首个，旨在评估在种植治疗中应用CGF的潜在结果。在PubMed和谷歌学术上进行了文献检索，查找2001年至2019年间发表的文章，使用了诸如“CGF”“牙种植体”“骨再生”“CGF”和“骨整合”等各种关键词。研究筛选按照PRISMA指南进行。本综述共纳入了11项研究。大多数纳入研究表明CGF在种植治疗中具有有益作用。CGF被认为可促进骨整合并增强骨再生。尽管从长远来看需要更多临床研究来验证CGF的潜在优点，但初步结果似乎很有前景。
