Imamura Masayuki
Kyoto University, Director Osaka Saiseikai Noe Hospital, Osaka, Japan.
Nihon Geka Gakkai Zasshi. 2005 Aug;106(8):472-8.
Recent strategies for the treatment of pancreatic endocrine tumors are described. Most cases are metastatic, and liver metastasis is the most significant prognostic factor. Thus curative resection before liver metastasis develops based on the localization of the tumors with the SASI test is the standard strategy. Subtotal distal pancreatectomy or pancreas-preserving total duodenectomy is indicated for multiple pancreatic endocrine tumors and multiple duodenal gastrinomas, respectively, for patients with multiple endocrine neoplasia type 1.
本文描述了胰腺内分泌肿瘤的最新治疗策略。大多数病例为转移性，肝转移是最重要的预后因素。因此，基于SASI试验对肿瘤进行定位，在肝转移发生前进行根治性切除是标准策略。对于1型多发性内分泌腺瘤患者，分别行远端胰腺次全切除术或保留胰腺的全十二指肠切除术治疗多发性胰腺内分泌肿瘤和多发性十二指肠胃泌素瘤。
