Delongchamps Nicolas Barry, Mao Kaili, Theng Hang, Zerbib Marc, Debré Bernard, Peyromaure Michaël
Department of Urology, Cochin Hospital, Service d'Urologie, Paris, France.
Eur Urol. 2005 Dec;48(6):946-50. doi: 10.1016/j.eururo.2005.07.008. Epub 2005 Aug 2.
To analyze the outcome of patients after fortuitous diagnosis of prostate cancer (PCa) on cystoprostatectomy (CPT) specimen.
The medical charts of 141 male patients who underwent radical CPT for urothelial cell carcinoma of the bladder between january 1995 and april 2000 were retrospectively reviewed. None of the patients had preoperative clinical or biological suspicion of PCa.
Pathological examination of the CPT specimens showed PCa in 20 patients (14.2%). Of these, 6 had a microfocal PCa, 10 had a pT2a tumour, 2 had a pT2b tumour, and 2 had a pT3a tumour. The Gleason score was < or =5 in 5 cases, 6 in 13 cases, and 7 in 2 cases. Two patients were lost to follow-up. Ten patients died of bladder cancer after a median follow-up of 13 months. Eight patients remained free of disease after a median follow-up of 64.5 months. None of the 20 patients experienced PCa recurrence during follow-up.
In our experience, the rate of unsuspected PCa on cystoprostatectomy specimens was 14.2%. The majority of these PCas were organ-confined, and there was no PCa recurrence during follow-up.
分析在膀胱前列腺切除术（CPT）标本上偶然诊断出前列腺癌（PCa）的患者的预后情况。
回顾性分析1995年1月至2000年4月期间141例因膀胱尿路上皮癌接受根治性CPT的男性患者的病历。所有患者术前均无PCa的临床或生物学可疑迹象。
CPT标本的病理检查显示20例患者（14.2%）患有PCa。其中，6例为微灶性PCa，10例为pT2a肿瘤，2例为pT2b肿瘤，2例为pT3a肿瘤。Gleason评分≤5分的有5例，6分的有13例，7分的有2例。2例患者失访。10例患者在中位随访13个月后死于膀胱癌。8例患者在中位随访64.5个月后无疾病复发。20例患者在随访期间均未出现PCa复发。
根据我们的经验，膀胱前列腺切除标本上意外发现PCa的发生率为14.2%。这些PCa大多数局限于器官内，随访期间无PCa复发。
