Cameron Mary Ann, Sakhaee Khashayar, Moe Orson W
Charles and Jane Pak Center for Mineral Metabolism and Clinical Research and Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-8885, USA.
Pediatr Nephrol. 2005 Nov;20(11):1587-92. doi: 10.1007/s00467-005-1883-z. Epub 2005 Aug 23.
A metabolic etiology is the most common cause for pediatric kidney stones. Appropriate evaluation of affected children should include assessment of stone type, if available, and assessment of predisposing factors in all cases. This review discusses the metabolic disorders that lead to nephrolithiasis with respect to the development of calcium, uric acid, struvite, and cystine stones. Environmental and hereditary factors are summarized to provide a guide in the evaluation of pediatric stone formers.
代谢病因是小儿肾结石最常见的病因。对患病儿童进行适当评估应包括评估结石类型(若可获取),以及对所有病例进行易感因素评估。本综述讨论了导致肾结石形成的代谢紊乱,涉及钙、尿酸、鸟粪石和胱氨酸结石的形成。总结了环境和遗传因素,为评估小儿结石形成者提供指导。