Ike R W, Arnold W J, Rothschild E W, Shaw H L
Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor 48109-0358.
J Rheumatol. 1992 May;19(5):772-9.
To determine the efficacy of tidal knee irrigation for knee pain due to osteoarthritis (OA), we conducted a randomized, single blind, 14-week prospective trial comparing medical management with tidal knee irrigation in 77 patients with non-end stage OA of the knee and unilateral pain refractory to standard medical treatment. Fifty-seven patients completed the study. Statistically significant differences (p less than 0.05) favoring tidal knee irrigation over medical management were pain after 50' walk, pain after 4-stair climb, most intense pain in previous day, frequency of knee stiffness with inactivity, days of morning knee stiffness in previous week, physician assessment of knee tenderness and overall assessments of therapy effectiveness by both patient and physician. Tidal knee irrigation results in more favorable improvement of pain due to OA than can be accomplished with traditional medical management.
为确定潮式膝关节冲洗治疗骨关节炎（OA）所致膝关节疼痛的疗效，我们进行了一项随机、单盲、为期14周的前瞻性试验，比较了77例非终末期膝关节OA且单侧疼痛对标准药物治疗无效的患者接受药物治疗与潮式膝关节冲洗的效果。57例患者完成了研究。与药物治疗相比，潮式膝关节冲洗在统计学上有显著差异（p小于0.05），具体体现在步行50米后的疼痛、爬4级楼梯后的疼痛、前一天的最剧烈疼痛、膝关节静止时僵硬的频率、前一周早晨膝关节僵硬的天数、医生对膝关节压痛的评估以及患者和医生对治疗效果的总体评估。与传统药物治疗相比，潮式膝关节冲洗能更有效地改善OA所致的疼痛。
