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一系列腹腔镜可调节胃束带术的长期结果与胃食管反流

Long-term results and gastroesophageal reflux in a series of laparoscopic adjustable gastric banding.

作者信息

Gutschow Christian A, Collet Peter, Prenzel Klaus, Hölscher Arnulf H, Schneider Paul M

机构信息

Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany.

出版信息

J Gastrointest Surg. 2005 Sep-Oct;9(7):941-8. doi: 10.1016/j.gassur.2005.02.001.

DOI:10.1016/j.gassur.2005.02.001
PMID:16137589
Abstract

During the past decade, laparoscopic adjustable gastric banding has become the most popular surgical procedure in treating morbid obesity. On the other hand, significant drawbacks such as inadequate long-term weight loss, a high prevalence of reoperations, and frequent postoperative symptoms have been reported in the literature. This analysis summarizes our Department's experience with this operation. Thirty-one patients (27 women and 4 men) with a mean body mass index of 46.5 kg/m(2) (range, 38.3-59.8 kg/m(2)) were operated upon laparoscopically between September 1997 and January 2003. The preoperative work-up of all patients included a psychological evaluation. Mean follow-up was 59.3 months (range, 19-84 months). Sixteen patients had esophageal pH-metry and 18 patients had upper gastrointestinal endoscopy preoperatively and postoperatively. Data were collected prospectively during the outpatient visits. Mean preoperative excess weight was 65.6 kg (range, 37.4-96.1 kg). Mean excess weight loss after 12, 24, 36, 48, 60, 72, and 84 months was 40.3%, 50.5%, 51.9%, 48.9%, 46.2%, 51.8%, and 30.2%, respectively. In total, six patients (19.4%) had an abdominal reoperation, including four patients (12.9%) for band removal. Upper gastrointestinal endoscopy was performed in 18 patients after 30.1 months (range, 5-67 months), showing a high prevalence of esophagitis (30.0%; grade 1: n=3, grade 2: n=3). Conversely, postoperative esophageal pH-metry performed in 16 patients was pathologic in 43.8%. Laparoscopic adjustable gastric banding produces significant weight loss even after long-term follow-up. However, the reoperation rate is high and postoperative symptoms are frequent. The high incidence of gastroesophageal reflux and esophagitis remains a matter of concern.

摘要

在过去十年中,腹腔镜可调节胃束带术已成为治疗病态肥胖最常用的外科手术。另一方面,文献报道了一些显著的缺点,如长期体重减轻不足、再次手术发生率高以及术后症状频繁。本分析总结了我们科室开展该手术的经验。1997年9月至2003年1月期间,对31例患者(27例女性和4例男性)进行了腹腔镜手术,平均体重指数为46.5kg/m²(范围为38.3 - 59.8kg/m²)。所有患者术前均进行了心理评估。平均随访时间为59.3个月(范围为19 - 84个月)。16例患者进行了食管pH值测定,18例患者术前和术后进行了上消化道内镜检查。数据在门诊随访期间前瞻性收集。术前平均超重65.6kg(范围为37.4 - 96.1kg)。术后12、24、36、48、60、72和84个月时,平均超重减轻分别为40.3%、50.5%、51.9%、48.9%、46.2%、51.8%和30.2%。共有6例患者(19.4%)进行了腹部再次手术,其中4例患者(12.9%)进行了束带拆除。18例患者在30.1个月(范围为5 - 67个月)后进行了上消化道内镜检查,食管炎发生率较高(30.0%;1级:n = 3,2级:n = 3)。相反,16例患者术后进行的食管pH值测定结果显示,43.8%为病理性。即使经过长期随访,腹腔镜可调节胃束带术仍能显著减轻体重。然而,再次手术率较高,术后症状频繁。胃食管反流和食管炎的高发生率仍然令人担忧。

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Obes Surg. 2004 Aug;14(7):986-90. doi: 10.1381/0960892041719545.
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Long-term results, late complications and quality of life in a series of adjustable gastric banding.一系列可调节胃束带术的长期结果、晚期并发症及生活质量
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The influence of laparoscopic adjustable gastric banding on gastroesophageal reflux.
腹腔镜可调节胃束带术后常规上消化道系列筛查和监测的结果。
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Upper Gastrointestinal Function in Morbidly Obese Adolescents Before and 6 Months After Gastric Banding.肥胖青少年胃带手术后 6 个月前后的上消化道功能。
Obes Surg. 2018 May;28(5):1277-1288. doi: 10.1007/s11695-017-3000-3.
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Laparoscopic Nissen Fundoplication Plus Mid-gastric Plication for Treatment of Obese Patients with Gastroesophageal Reflux Disease.腹腔镜下尼氏胃底折叠术联合胃中部折叠术治疗肥胖型胃食管反流病患者
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