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肥胖的胃食管诊断检查:国际食管疾病学会的立场声明。

Gastro-esophageal diagnostic workup before bariatric surgery or endoscopic treatment for obesity: position statement of the International Society of Diseases of the Esophagus.

机构信息

Gastroenterology Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

Digestive Endoscopy Unit, Pisa University Hospital, Pisa, Italy.

出版信息

Dis Esophagus. 2024 Apr 27;37(5). doi: 10.1093/dote/doae006.

Abstract

Obesity is a chronic and multifactorial condition characterized by abnormal weight gain due to excessive adipose tissue accumulation that represents a growing worldwide challenge for public health. In addition, obese patients have an increased risk of hiatal hernia, esophageal, and gastric dysfunction, as well as gastroesophageal reflux disease, which has a prevalence over 40% in those seeking endoscopic or surgical intervention. Surgery has been demonstrated to be the most effective treatment for severe obesity in terms of long-term weight loss, comorbidities, and quality of life improvements and overall mortality decrease. The recent emergence of bariatric endoscopic techniques promises less invasive, more cost-effective, and reproducible approaches to the treatment of obesity. With the endorsement of the International Society for Diseases of the Esophagus, we started a Delphi process to develop consensus statements on the most appropriate diagnostic workup to preoperatively assess gastroesophageal function before bariatric surgical or endoscopic interventions. The Consensus Working Group comprised 11 international experts from five countries. The group consisted of gastroenterologists and surgeons with a large expertise with regard to gastroesophageal reflux disease, bariatric surgery and endoscopy, and physiology. Ten statements were selected, on the basis of the agreement level and clinical relevance, which represent an evidence and experience-based consensus of the International Society for Diseases of the Esophagus.

摘要

肥胖是一种慢性多因素疾病,其特征是由于脂肪组织过度积累导致的异常体重增加,这是全球公共卫生面临的日益严峻的挑战。此外,肥胖患者患食管裂孔疝、食管和胃功能障碍以及胃食管反流病的风险增加,而这些患者在寻求内镜或手术干预时,患病率超过 40%。手术已被证明是治疗重度肥胖症最有效的方法,可长期减轻体重、改善合并症和生活质量,并降低总体死亡率。最近出现的减重内镜技术有望为肥胖症的治疗提供更微创、更具成本效益且可重复的方法。在国际食管疾病学会的支持下,我们启动了一项 Delphi 流程,以制定共识声明,就肥胖症手术或内镜干预前评估胃食管功能的最合适的诊断方案达成共识。共识工作组由来自五个国家的 11 名国际专家组成。该小组由胃肠病学家和外科医生组成,他们在胃食管反流病、减重手术和内镜以及生理学方面拥有丰富的专业知识。根据一致性水平和临床相关性,选择了 10 项声明,这些声明代表了国际食管疾病学会基于证据和经验的共识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f17/11919618/9f2bf32594ed/doae006f1.jpg

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