Hussain Nazimul, Hussain Anjli, Natarajan Sundaram
Aditya Jyot Eye Hospital, Mumbai, India.
Indian J Ophthalmol. 2005 Sep;53(3):183-6. doi: 10.4103/0301-4738.16677.
To evaluate the initial results of pilot study of indocyanine green dye enhanced laser photocoagulation for juxtafoveal choroidal neovascularisation (CNV).
The study was conducted on eleven eyes of 11 patients of CNV during the period 2001 and 2002. Two to three minutes after the injection of 5 ml of 25 mgm of indocyanine green (ICG) dye, 810 nm diode laser was used to treat the choroidal neovascular lesions.
The age of the patients ranged from 45 to 80 years. All patients completed 12 months of follow-up. Eight eyes (72.7%) had neovascular age related macular degeneration, 2 eyes (18.2%) had myopic CNV and one eye (9.09%) had CNV secondary to angioid streak. The presenting visual acuity was <or=6/60 in seven, 6/36 in one and >or=6/12 in three patients. The final visual acuity at the end of at least 12 months follow-up was 6/12 or better in one eye (9%); 6/18-6/36 in 3 eyes (27.27%) and <or=6/60 in 7 eyes (63.64%). In four patients the vision improved whereas it worsened or remained same in 7 eyes.
ICG dye enhanced diode laser photocoagulation appears to be a potential option for juxtafoveal CNV.
评估吲哚菁绿染料增强型激光光凝治疗近黄斑中心凹脉络膜新生血管（CNV）初步研究的初始结果。
2001年至2002年期间，对11例CNV患者的11只眼睛进行了研究。注射5毫升含25毫克吲哚菁绿（ICG）染料后两到三分钟，使用810纳米二极管激光治疗脉络膜新生血管病变。
患者年龄在45至80岁之间。所有患者均完成了12个月的随访。8只眼睛（72.7%）患有与年龄相关的新生血管性黄斑变性，2只眼睛（18.2%）患有近视性CNV，1只眼睛（9.09%）患有继发于血管样条纹的CNV。7例患者就诊时视力≤6/60，1例为6/36，3例≥6/12。至少12个月随访结束时，1只眼睛（9%）的最终视力为6/12或更好；3只眼睛（27.27%）为6/18 - 6/36，7只眼睛（63.64%）≤6/60。4例患者视力改善，7只眼睛视力恶化或保持不变。
吲哚菁绿染料增强型二极管激光光凝似乎是治疗近黄斑中心凹CNV的一种潜在选择。
