Marcos Luis, Maco Vicente, Terashima Angélica, Samalvides Frine, Espinoza José R, Gotuzzo Eduardo
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.
Rev Inst Med Trop Sao Paulo. 2005 Jul-Aug;47(4):219-22. doi: 10.1590/s0036-46652005000400008. Epub 2005 Aug 29.
High prevalence rates of human fascioliasis have been described in several regions of Peru. We surveyed 20 families in an endemic area of Peru in order to determine the proportion of infection with F. hepatica in relatives of diagnosed subjects and in order to identify associated risk factors. The study included feces and blood samples of 93 subjects. Ages ranged from one to 53 (mean = 18.6; SD = 14.2). The overall prevalence of fascioliasis by fecal examinations was 33.3% (n = 83) and by serology, 51.9% (n = 86). The prevalence in age group I (< or = 19 years old) by coprological and serological tests was 61.4% and 75.9%, respectively; in group II (> 19 years old) 15.4% and 37.5%. The main associated risk factor with fascioliasis was eating salads (OR = 3.29, CI = 1.2 - 9.0, p = 0.02). In conclusion, human fascioliasis is highly prevalent in the relatives of index cases and the most significant risk factor of acquiring fascioliasis in the family is eating salads in endemic areas.
秘鲁的几个地区已报告人类肝片吸虫病的高流行率。我们对秘鲁一个流行地区的20个家庭进行了调查，以确定确诊患者亲属中肝片吸虫感染的比例，并确定相关的危险因素。该研究纳入了93名受试者的粪便和血液样本。年龄范围为1至53岁（平均 = 18.6；标准差 = 14.2）。粪便检查显示肝片吸虫病的总体患病率为33.3%（n = 83），血清学检查为51.9%（n = 86）。通过粪便学和血清学检测，年龄组I（≤19岁）的患病率分别为61.4%和75.9%；年龄组II（>19岁）为15.4%和37.5%。与肝片吸虫病相关的主要危险因素是食用沙拉（比值比 = 3.29，可信区间 = 1.2 - 9.0，p = 0.02）。总之，人类肝片吸虫病在索引病例的亲属中高度流行，在流行地区家庭中感染肝片吸虫病的最重要危险因素是食用沙拉。
