McGrath C, Wong A H H, Lo E C M, Cheung C S
Faculty of Dentistry, University of Hong Kong, 34 Hospital Road, Hong Kong, China.
J Dent. 2005 Sep;33(8):697-702. doi: 10.1016/j.jdent.2005.01.012. Epub 2005 Mar 19.
To assess the sensitivity and responsiveness of an oral health related quality of life measure to tooth whitening.
Following screening at a clinic, 87 subjects were given an array of tooth whitening products to use at home and reviewed 8 weeks later. Subjects self-completed the 49-item Oral Health Impact Profile (OHIP) at baseline and follow-up, and rated their satisfaction with the whiteness of their teeth compared to baseline on a global transition scale.
In terms of sensitivity, observed changes were apparent in overall OHIP scores (P<0.05) and across several domains, notably functional limitation (P<0.01). However, the magnitude of change (effect size) was generally small except for the functional domain. There was an observed gradient in observed change in OHIP scores and in the magnitude of such changes (effect sizes) in relation to global rating of satisfaction with the outcome, supporting the responsiveness of the measure.
The OHIP scale is sensitive and responsive to the effects of tooth whitening. Greatest sensitivity and responsiveness was in relation to functional limitations. These findings have implications for the use of oral health related quality of life measures as an outcome measure of interventions aimed at improving dental aesthetics through tooth whitening.
评估一项与口腔健康相关的生活质量测量指标对牙齿美白的敏感性和反应性。
在一家诊所进行筛查后，87名受试者获得了一系列牙齿美白产品以便在家中使用，并在8周后接受复查。受试者在基线期和随访时自行完成49项的口腔健康影响程度量表（OHIP），并根据整体变化量表对牙齿美白程度与基线期相比的满意度进行评分。
在敏感性方面，OHIP总分（P<0.05）以及几个领域，尤其是功能受限领域（P<0.01）出现了明显的观察到的变化。然而，除功能领域外，变化幅度（效应量）通常较小。观察到OHIP得分的变化以及这些变化的幅度（效应量）与对结果的整体满意度评级之间存在梯度关系，这支持了该测量指标的反应性。
OHIP量表对牙齿美白的效果具有敏感性和反应性。最大的敏感性和反应性与功能受限有关。这些发现对于将与口腔健康相关的生活质量测量指标用作旨在通过牙齿美白改善牙齿美观的干预措施的结果测量指标具有启示意义。
