Park Byung Kwan, Kim Seung Hyup, Moon Min Hoan, Jung Sung Il
Department of Radiology, Seoul National University College of Medicine, Institute of Radiation Medicine, SNUMRC, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.
Korean J Radiol. 2005 Jul-Sep;6(3):179-84. doi: 10.3348/kjr.2005.6.3.179.
To characterize the imaging features on gray-scale and contrast-enhanced color Doppler US images which differentiate renal ischemia from renal infarction.
The segmental renal arteries of eight healthy rabbits were surgically ligated. In four of these rabbits, the ligated renal artery was released 60 minutes after arterial occlusion to cause transient ischemia. In the remaining four rabbits, the arterial ligation was retained to cause a permanent infarction. The gray-scale and contrast-enhanced color Doppler US imaging features of the involved renal parenchyma of both ischemia and infarction groups were compared with respect to the presence or absence of parenchymal swelling, echogenicity changes, tissue loss and perfusion defects.
Parenchyma swelling, echogenic changes, tissue loss and perfusion defects were found to be more extensive in the infarction than the ischemia group. The hyperechoic areas reperfused with blood flow recovered normal echogenicity and perfusion, whereas the hyperechoic areas without reperfusion became renal infarcts.
Gray-scale and contrast-enhanced color Doppler US showed that the hyperechoic areas with reperfusion may reverse to normal parenchyma and allow the differentiation of renal ischemia from renal infarction.
描述灰阶及对比增强彩色多普勒超声图像上区分肾缺血与肾梗死的成像特征。
对8只健康兔的肾段动脉进行手术结扎。其中4只兔在动脉闭塞60分钟后松开结扎的肾动脉，造成短暂性缺血。其余4只兔保留动脉结扎，造成永久性梗死。比较缺血组和梗死组受累肾实质的灰阶及对比增强彩色多普勒超声成像特征，观察实质肿胀、回声改变、组织缺失和灌注缺损情况。
发现梗死组的实质肿胀、回声改变、组织缺失和灌注缺损比缺血组更广泛。血流再灌注的高回声区回声和灌注恢复正常，而无再灌注的高回声区则成为肾梗死灶。
灰阶及对比增强彩色多普勒超声显示，有再灌注的高回声区可恢复为正常实质，有助于区分肾缺血与肾梗死。
