睾丸癌生物学及I期和双侧疾病管理的当前概念探讨。

A discussion of the biology of testicular cancer and current concepts in the management of stage I and bilateral disease.

作者信息

Coffey J, Birtle A J, Cogill G, Christmas T J, Rapley E A, Huddart R A

机构信息

Academic Urology Unit, Royal Marsden Hospital, Sutton, UK.

出版信息

Clin Oncol (R Coll Radiol). 2005 Sep;17(6):441-7. doi: 10.1016/j.clon.2005.05.008.

DOI:10.1016/j.clon.2005.05.008

PMID:16149288

Abstract

This case was the subject of a Grand Round Presentation at the Royal Marsden Hospital, Sutton, UK on 8 June 2004. A case of metachronous, bilateral testicular germ-cell tumours (TGCTs) arising in a patient with a family history of this disease was presented. The second primary was managed conservatively. The rationale and outcome of this approach was presented, along with a discussion of the management of early stage TGCTs and the genetics of familial and bilateral disease.

摘要

该病例是2004年6月8日在英国萨顿皇家马斯登医院举行的一次全院大查房汇报的主题。汇报了一名有该疾病家族史的患者发生异时性双侧睾丸生殖细胞肿瘤（TGCTs）的病例。对第二个原发性肿瘤采取了保守治疗。介绍了这种治疗方法的基本原理和结果，同时讨论了早期TGCTs的治疗以及家族性和双侧性疾病的遗传学。