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[碘化对氯化自来水总致突变活性的影响]

[Impact of iodination on the total mutagenic activity of chlorinated tap water].

作者信息

Akhal'tseva L V, Zhukov V S, Kir'ianova L F, Neiaskina E V, Ryzhova I N, Sevost'ianova E M

出版信息

Gig Sanit. 2005 Jul-Aug(4):18-20.

PMID:16149302
Abstract

The impact of iodination on the total mutagenic activity (TMA) of chlorinated tap water was studied. Iodination was made, by using iodine in doses of 0.5 to 4.0 mg/l on an experimental unit at pH 7.3-7.5 for 30 min. Organic water pollutants were concentrated, by using the polymer sorbent Separon SE. The mutagenic activity of water concentrates was evaluated in the Ames test using the strains Salmonella TA 100 and TA 98 both in the presence and in the absence of the metabolic activation system. Iodination substantially reduced the TMA of chlorinated tap water. The minimally effective dose of iodine against the TMA of chlorinated tap water was 1 mg/l, as evidenced by the tests using all the strains/variants and 0.5 mg/l, as shown by the tests using the strain TA 100 in the variant without metabolic activation.

摘要

研究了碘化对氯化自来水总致突变活性(TMA)的影响。通过在pH 7.3 - 7.5的实验单元中使用剂量为0.5至4.0 mg/l的碘进行碘化处理30分钟。使用聚合物吸附剂Separon SE浓缩有机水污染物。在有无代谢活化系统的情况下,使用沙门氏菌TA 100和TA 98菌株在艾姆斯试验中评估水浓缩物的致突变活性。碘化显著降低了氯化自来水的TMA。对抗氯化自来水TMA的碘的最低有效剂量为1 mg/l(使用所有菌株/变体的测试证明),以及0.5 mg/l(在无代谢活化变体中使用TA 100菌株的测试显示)。

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