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莫氏显微外科手术后的癌症复发:肿瘤持续存在的一种机制。

Cancer recurrence following Mohs micrographic surgery: a mechanism of tumor persistence.

作者信息

Eliezri Y D, Cohen P R

机构信息

Department of Dermatology, College of Physicians and Surgeons of Columbia University, New York, NY.

出版信息

Plast Reconstr Surg. 1992 Jul;90(1):121-5. doi: 10.1097/00006534-199207000-00020.

DOI:10.1097/00006534-199207000-00020
PMID:1615072
Abstract

Recurrence of basal cell carcinomas after Mohs micrographic surgery is rare but known to occur. This report describes the recurrence of a basal cell carcinoma of the forehead after Mohs surgery in order to illustrate a previously undescribed mechanism of tumor persistence and recurrence despite thorough microscopic evaluation of all surgical margins. The value of the surgeon's reviewing all prior histologic sections before performing micrographic surgery, the importance of resecting all scar tissue from a previous surgical site prior to determination of tumor-free margins, and the potential usefulness of a three-tiered closure after excision of a cutaneous malignancy that involves the muscular layer are discussed.

摘要

莫氏显微外科手术后基底细胞癌复发罕见但确有发生。本报告描述了一例前额基底细胞癌在莫氏手术后的复发情况,以阐明一种此前未被描述的肿瘤持续存在和复发机制,尽管对所有手术切缘进行了全面的显微镜评估。文中还讨论了外科医生在进行显微外科手术前复查所有先前组织学切片的价值、在确定无瘤切缘之前从先前手术部位切除所有瘢痕组织的重要性,以及切除累及肌肉层的皮肤恶性肿瘤后采用三层缝合的潜在作用。

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Cancer recurrence following Mohs micrographic surgery: a mechanism of tumor persistence.莫氏显微外科手术后的癌症复发:肿瘤持续存在的一种机制。
Plast Reconstr Surg. 1992 Jul;90(1):121-5. doi: 10.1097/00006534-199207000-00020.
2
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Acta Derm Venereol. 2011 Oct;91(6):689-93. doi: 10.2340/00015555-1134.
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[Mohs micrographic surgery for repeat excision of basal cell carcinomas on the head with positive margins].[莫氏显微外科手术用于头部基底细胞癌切缘阳性的重复切除]
Actas Dermosifiliogr. 2011 Dec;102(10):797-804. doi: 10.1016/j.ad.2011.03.020.
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Acta Derm Venereol. 1999 Sep;79(5):370-2. doi: 10.1080/000155599750010292.
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Post-Mohs micrographic surgical margin tissue evaluation with permanent histopathologic sections.采用永久性组织病理学切片对莫氏显微外科手术切缘组织进行评估。
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Mohs' micrographic surgery for basal-cell carcinoma of the face.面部基底细胞癌的莫氏显微外科手术。
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[Application of Mohs microsurgery in nasal basal cell carcinoma].[莫氏显微外科手术在鼻基底细胞癌中的应用]
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Acta Derm Venereol. 2024 Apr 2;104:15765. doi: 10.2340/actadv.v104.15765.
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