Lequin Maarten H, Vermeulen Jeroen R, van Elburg Ruurd M, Barkhof Frederik, Kornelisse René F, Swarte Renate, Govaert Paul P
Department of Radiology, Sophia Children's Hospital, Erasmus MC--University Medical Center, Rotterdam, the Netherlands.
AJNR Am J Neuroradiol. 2005 Sep;26(8):2137-43.
Meningoencephalitis can severely damage the developing brain. Preterms are more prone for nosocomial infections with pathogens other than Group B streptococci and Escherichia coli. In this report we focus on the deleterious clinical course and imaging characteristics of proven Bacillus cereus meningoencephalitis.
We collected 3 cases of proven Bacillus cereus meningoencephalitis. In the medical records we focused on prenatal, perinatal, and postnatal risk factors. Imaging data of several brain ultrasounds, MR images, and diffusion-weighted images were reevaluated.
The ultrasound and MR images show a typical pattern of mainly hemorrhagic and early cavitating, selective white matter destruction.
Knowledge of this paradigm of acquired brain injury may help to better understand the natural course of these severe neonatal infections.
脑膜脑炎可严重损害发育中的大脑。早产儿更容易发生由B族链球菌和大肠杆菌以外的病原体引起的医院感染。在本报告中，我们重点关注已证实的蜡样芽孢杆菌脑膜脑炎的有害临床病程和影像学特征。
我们收集了3例已证实的蜡样芽孢杆菌脑膜脑炎病例。在病历中，我们重点关注产前、围产期和产后的危险因素。对多次脑部超声、磁共振成像（MR）和扩散加权成像的影像数据进行了重新评估。
超声和MR图像显示出一种典型模式，主要为出血性和早期空洞形成，选择性白质破坏。
了解这种获得性脑损伤模式可能有助于更好地理解这些严重新生儿感染的自然病程。
