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早产儿神经影像学与神经发育结局:重点关注脑室周围出血、出血后脑积水及相关脑损伤。

Preterm neuroimaging and neurodevelopmental outcome: a focus on intraventricular hemorrhage, post-hemorrhagic hydrocephalus, and associated brain injury.

机构信息

Division of Perinatal-Neonatal Medicine, Department of Pediatrics, The Johns Hopkins School of Medicine, Baltimore, MD, USA.

Neurosciences Intensive Care Nursery, The Johns Hopkins School of Medicine, Baltimore, MD, USA.

出版信息

J Perinatol. 2018 Nov;38(11):1431-1443. doi: 10.1038/s41372-018-0209-5. Epub 2018 Aug 30.

Abstract

Intraventricular hemorrhage in the setting of prematurity remains the most common cause of acquired hydrocephalus. Neonates with progressive post-hemorrhagic hydrocephalus are at risk for adverse neurodevelopmental outcomes. The goal of this review is to describe the distinct and often overlapping types of brain injury in the preterm neonate, with a focus on neonatal hydrocephalus, and to connect injury on imaging to neurodevelopmental outcome risk. Head ultrasound and magnetic resonance imaging findings are described separately. The current state of the literature is imprecise and we end the review with recommendations for future radiologic and neurodevelopmental research.

摘要

脑室出血是早产儿最常见的获得性脑积水的原因。患有进行性出血后脑积水的新生儿有发生不良神经发育结局的风险。本综述的目的是描述早产儿中不同且常重叠的脑损伤类型,重点是新生儿脑积水,并将影像学上的损伤与神经发育结局风险联系起来。分别描述了头部超声和磁共振成像的发现。目前的文献状态并不精确,因此我们在综述的最后提出了未来放射学和神经发育研究的建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7352/6215507/c7e79e769e27/nihms-990730-f0001.jpg

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