Huisman Thierry A G M, Boltshauser Eugen, Martin Ernst, Nadal David
Department of Diagnostic Imaging ,University Children's Hospital Zurich, Zurich, Switzerland.
AJNR Am J Neuroradiol. 2005 Sep;26(8):2153-6.
Progressive multifocal leukoencephalopathy is a severe demyelinating disease of the central nervous system caused by a JC papovavirus infection. Prognosis is poor with fatal outcome within 1 year in 90% of patients. Our case report shows that diffusion tensor imaging can give early and specific information about disease status and extent in a 15-year-old girl with progressive multifocal leukoencephalopathy associated with congenital human immunodeficiency virus (HIV) infection.
进行性多灶性白质脑病是一种由JC多瘤病毒感染引起的严重中枢神经系统脱髓鞘疾病。90%的患者预后较差，1年内会有致命后果。我们的病例报告显示，弥散张量成像可为一名15岁患有与先天性人类免疫缺陷病毒（HIV）感染相关的进行性多灶性白质脑病女孩的疾病状态和范围提供早期和特异性信息。
