Division Pediatric Radiology, Johns Hopkins Hospital, Baltimore, MD 21287-0842, USA.
Cancer Imaging. 2010 Oct 4;10 Spec no A(1A):S163-71. doi: 10.1102/1470-7330.2010.9023.
Diffusion-weighted and diffusion tensor imaging (DWI/DTI) has revolutionized clinical neuroimaging. Pathology may be detected earlier and with greater specificity than with conventional magnetic resonance imaging sequences. In addition, DWI/DTI allows exploring the microarchitecture of the brain. A detailed knowledge of the basics of DWI/DTI is mandatory to better understand pathology encountered and to avoid misinterpretation of typical DWI/DTI artifacts. This article reviews the basic physics of DWI/DTI exemplified by several classical clinical cases.
弥散加权和弥散张量成像(DWI/DTI)已经彻底改变了临床神经影像学。与传统的磁共振成像序列相比,它可以更早、更具特异性地检测到病变。此外,DWI/DTI 还可以探索大脑的微观结构。为了更好地理解遇到的病变并避免对典型 DWI/DTI 伪影的误解,必须深入了解 DWI/DTI 的基础知识。本文通过几个经典的临床病例,举例说明了 DWI/DTI 的基本物理学原理。