Awadalla A W, Ohaeri J U, Salih A A, Tawfiq A M
Department of Psychiatry, Faculty of Medicine, Kuwait University, Kuwait.
Qual Life Res. 2005 Oct;14(8):1855-67. doi: 10.1007/s11136-005-4328-z.
Researchers have paid scant attention to comparative studies of quality of life (QOL) issues among psychiatric diagnostic groups; the studies of patient-caregiver concordance ratings had small sample sizes; and the reports are rare from the African and Arab worlds.
to assess the subjective QOL of stable Sudanese outpatients, using the WHOQOL-Bref, compared with a general population sample; examine the caregiver-patient concordance; and assess the variables that impact on domains of QOL.
The responses of outpatients with schizophrenia (99), major affective disorders (120) and neuroses (81) (mean age 33.8) were compared with 211 controls and the impression of their family caregivers.
Patients were dissatisfied with life circumstances; the schizophrenia group and those with co-morbidity had significantly lower QOL scores; while the control group had higher QOL scores. There was no significant impact on QOL domains, of socio-demographic factors, duration of illness and treatment side effects. The schizophrenia group had least concordance with caregivers, but eight items were judged to be satisfactorily concordant for all groups.
Psychiatric patients in stable condition can make reliable judgments of QOL, with relatives providing additional information. Differences in QOL and concordance of ratings reflect disease severity.
研究人员很少关注精神科诊断组之间生活质量（QOL）问题的比较研究；患者与照顾者一致性评分的研究样本量较小；来自非洲和阿拉伯世界的相关报告也很罕见。
使用世界卫生组织生活质量简表（WHOQOL-Bref）评估苏丹稳定期门诊患者的主观生活质量，并与普通人群样本进行比较；检查照顾者与患者的一致性；评估影响生活质量领域的变量。
将精神分裂症门诊患者（99例）、重度情感障碍患者（120例）和神经症患者（81例）（平均年龄33.8岁）的回答与211名对照组人员及其家庭照顾者的印象进行比较。
患者对生活状况不满意；精神分裂症组和合并症患者的生活质量得分显著较低；而对照组的生活质量得分较高。社会人口学因素、病程和治疗副作用对生活质量领域没有显著影响。精神分裂症组与照顾者的一致性最低，但所有组中有八项被判定为一致性良好。
病情稳定的精神科患者能够对生活质量做出可靠的判断，亲属可提供额外信息。生活质量和评分一致性的差异反映了疾病的严重程度。
