Tan C S H, Lim T H, Koh W P, Liew G C, Hoh S T, Tan C C, Au Eong K G
The Eye Institute at Tan Tock Seng Hospital, National Healthcare Group, Singapore.
Eye (Lond). 2006 Aug;20(8):908-12. doi: 10.1038/sj.eye.6702046. Epub 2005 Sep 16.
To describe the epidemiology of pterygium among residents of an island in Indonesia and to examine the roles of age and gender as determinants of bilaterality and severity of the disease.
Voluntary eye screening on Pulau Jaloh, Riau Archipelago, Indonesia. Gender difference was tested using the chi2 test. The difference in age between subjects with and without disease was tested using unpaired Student's t-test. Odds ratio (relative risk) for gender was calculated using logistic regression model with adjustment for age.
Of the 550 inhabitants, 477 (86.7%) responded to the eye screening. The overall prevalence rate of pterygium was 17.0%. Out of 211, 48 male (22.7%) and 33 out of 266 female subjects (12.4%) had the disorder, with the gender difference being statistically significant. Adjusted for age, the risk of disease was 3.1-fold higher among the males. In all, 71.6% of subjects with pterygium had bilateral disease. Subjects with pterygium were significantly older, their mean age being 42.9 years compared to 18.7 years among those without disease. The prevalence rates in male subjects increased from age 20 to reach a plateau of 63.6% at age 35 and remained stable thereafter. In the female subjects, the rates also increased with age, albeit at a slower rate, from age 20 to reach a plateau of 46.7% at age 55 and remained stable thereafter.
There is a high prevalence rate of pterygium among the study subjects, with the rates increasing rapidly with age.
描述印度尼西亚一座岛屿居民中翼状胬肉的流行病学特征，并探讨年龄和性别作为该疾病双侧性和严重程度决定因素的作用。
在印度尼西亚廖内群岛的贾洛岛进行自愿眼部筛查。使用卡方检验检测性别差异。使用非配对学生t检验检测患病与未患病受试者之间的年龄差异。使用逻辑回归模型并对年龄进行调整来计算性别的优势比（相对风险）。
550名居民中，477人（86.7%）响应了眼部筛查。翼状胬肉的总体患病率为17.0%。在211名男性受试者中，48人（22.7%）患病；在266名女性受试者中，33人（12.4%）患病，性别差异具有统计学意义。经年龄调整后，男性患病风险高3.1倍。总体而言，71.6%的翼状胬肉受试者患有双侧疾病。患有翼状胬肉的受试者年龄显著更大，其平均年龄为42.9岁，而未患病者的平均年龄为18.7岁。男性受试者的患病率从20岁开始上升，在35岁时达到63.6%的平台期，此后保持稳定。在女性受试者中，患病率也随年龄增加，尽管增速较慢，从20岁开始，在55岁时达到46.7%的平台期，此后保持稳定。
研究对象中翼状胬肉患病率较高，且患病率随年龄迅速增加。
