Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 1 Shuaifu Yuan, Dongcheng District, Beijing, 100730, China.
Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College, Beijing, China.
BMC Ophthalmol. 2020 Feb 3;20(1):45. doi: 10.1186/s12886-020-1324-6.
To investigate the prevalence of pterygium and associated factors in Han and Mongolian adults at four survey sites in Inner Mongolia, China.
We conducted a population-based, cross-sectional study as part of the China National Health Survey (CNHS). By means of a stratified sampling method, we finally included 2651 participants of 30 years of age or older from a total of 3468 eligible residents. Factors associated with pterygium were analysed by a univariate analysis and logistic regression models.
The study population included 1910 Han and 741 Mongolian adults. The mean age ± standard deviation of the study cohort was 48.93 ± 11.06 years. The overall prevalence of pterygium was 6.4% (n = 169); 1.4% (n = 38) of the cases were bilateral and 4.8% (n = 128) were unilateral. The most common grade of pterygium was Grade 2. Based on the results of the univariate analysis, eleven factors were included in a multivariate analysis. The results indicated that age (P < 0.001), outdoor occupation (P = 0.026), and time spent in rural areas (P < 0.001) were significantly associated with pterygium. Sex and ethnicity were not identified as risk factors.
Our results indicated that outdoor occupation, old age and more time spent in rural areas were risk factors for pterygium in Inner Mongolia. At the same time, town as a survey site (Hohhot and Tsining District) was a protective factor for pterygium. Ethnicity, gender, smoking, diabetes and high blood pressure are not associated with pterygium.
为了调查中国内蒙古四个调查点汉族和蒙古族成年人中翼状胬肉的患病率及其相关因素。
我们进行了一项基于人群的横断面研究,作为中国国家健康调查(CNHS)的一部分。通过分层抽样方法,我们最终从总共 3468 名合格居民中纳入了 2651 名 30 岁或以上的参与者。通过单因素分析和逻辑回归模型分析与翼状胬肉相关的因素。
研究人群包括 1910 名汉族和 741 名蒙古族成年人。研究队列的平均年龄±标准差为 48.93±11.06 岁。翼状胬肉的总患病率为 6.4%(n=169);38 例(1.4%)为双侧,128 例(4.8%)为单侧。翼状胬肉最常见的等级为 2 级。基于单因素分析的结果,有 11 个因素纳入多因素分析。结果表明,年龄(P<0.001)、户外职业(P=0.026)和在农村地区的时间(P<0.001)与翼状胬肉显著相关。性别和种族不是危险因素。
我们的结果表明,户外职业、年龄较大和在农村地区的时间较长是内蒙古翼状胬肉的危险因素。同时,城镇作为调查点(呼和浩特和磁宁区)是翼状胬肉的保护因素。种族、性别、吸烟、糖尿病和高血压与翼状胬肉无关。