Ilkhanoff Leonard, O'Donnell Christopher J, Camargo Carlos A, O'Halloran T David, Giugliano Robert P, Lloyd-Jones Donald M
Cardiovascular Division, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Am J Cardiol. 2005 Sep 15;96(6):773-7. doi: 10.1016/j.amjcard.2005.04.059.
In a cohort of 710 patients with acute coronary syndromes (ACSs), we demonstrated that the Thrombolysis In Myocardial Infarction Risk Index--a predictor of 30-day mortality in clinical trial patients with ST-elevation myocardial infarction (STEMI)--is a strong predictor of short- and long-term mortality with good discrimination ability (c statistics 0.77 to 0.79) among all subtypes of ACSs (STEMI, non-STEMI, and unstable angina pectoris). These results verify the utility of the Risk Index in unselected patients with STEMI, broaden its application to other types of ACSs, and extend its utility to stratification of long-term mortality risk.
在一个由710例急性冠状动脉综合征（ACS）患者组成的队列中，我们证明了心肌梗死溶栓风险指数（在ST段抬高型心肌梗死（STEMI）临床试验患者中是30天死亡率的预测指标）在所有ACS亚型（STEMI、非STEMI和不稳定型心绞痛）中是短期和长期死亡率的有力预测指标，且具有良好的区分能力（c统计量为0.77至0.79）。这些结果证实了风险指数在未经选择的STEMI患者中的实用性，将其应用范围扩大到其他类型的ACS，并将其用于长期死亡风险分层的效用也进行了扩展。
