1例浸润性宫颈癌经全身化疗及锥切术后成功妊娠的病例。
A case of successful pregnancy after treatment of invasive cervical cancer with systemic chemotherapy and conization.
作者信息
Kobayashi Yaeko, Akiyama Futoshi, Hasumi Katuhiko
机构信息
Department of Gynecology and Pathology, Cancer Institute Hospital, 1-37-1 Kami-ikebukuro, Toshima-ku, Tokyo 170, Japan.
出版信息
Gynecol Oncol. 2006 Jan;100(1):213-5. doi: 10.1016/j.ygyno.2005.08.018. Epub 2005 Sep 19.
BACKGROUND
The standard therapy for invasive uterine cervical cancer causes loss of the woman's fertility. We report a successful pregnancy in a patient who desired fertility-sparing management of invasive cervical cancer and was treated with systemic chemotherapy and conization.
CASE
A 28-year-old nulliparous woman was diagnosed with a large 30-mm-diameter stage IB1 squamous cell carcinoma of the uterine cervix. The patient received 4 courses of systemic chemotherapy with consecutive low-dose BOMP (cisplatin, bleomycin, vincristine and mitomycin C), which produced complete pathological response assessed by examination of specimens from conization. Two years later, the patient became pregnant, resulting in the birth of a healthy infant.
CONCLUSION
This procedure is one method of conservative management to preserve fertility in invasive cervical cancer.
背景
浸润性子宫颈癌的标准治疗会导致女性丧失生育能力。我们报告了一例希望保留生育功能的浸润性宫颈癌患者，经全身化疗和锥切术治疗后成功妊娠。
病例
一名28岁未生育女性被诊断为直径30mm的IB1期子宫颈鳞状细胞癌。患者接受了4个疗程的连续低剂量BOMP（顺铂、博来霉素、长春新碱和丝裂霉素C）全身化疗，通过锥切标本检查评估产生了完全病理缓解。两年后，患者怀孕并诞下一名健康婴儿。
结论
该方法是保留浸润性宫颈癌患者生育功能的一种保守治疗方法。
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