Ramsey Deborah, Smithard David, Donaldson Nora, Kalra Lalit
Guy's, King's & St Thomas' School of Medicine, King's College, London, UK.
Dysphagia. 2005 Spring;20(2):105-7. doi: 10.1007/s00455-004-0024-3.
The goal of this study was to compare the diagnostic value of an absent gag reflex in acute stroke patients with the bedside swallowing assessment (BSA) and assess its relationship to outcomes. Two hundred forty-two acute stroke patients had their gag reflex tested and a BSA performed. Numbers needing nasogastric or gastrostomy tube insertion were noted, also their discharge destination, discharge Barthel Index, and mortality. The mean age of the subjects was 76.5+/-10.2 years; 37.6% were male; 41.7% of the patients were dysphagic on BSA; 18.2% had an absent gag. Dysphagia was present in 88.6% of the patients with an absent gag and in 31.3% of those with an intact gag. The gag reflex was absent in 38.6% of dysphagic and 3.5% of nondysphagic patients. Comparing an absent gag against the criterion of the BSA, its specificity was 0.96, sensitivity 0.39, positive predictive value 0.89, and negative predictive value 0.69. Regression analyses found that an intact gag gave an Odds Ratio [CI] of 0.23 [0.06-0.91] for gastrostomy feeding but did not predict other outcomes. We conclude that the gag reflex is as specific as but less sensitive than the BSA in detecting dysphagia in acute stroke patients. An intact gag may be protective against longer-term swallowing problems and the need for enteral feeding.
本研究的目的是比较急性卒中患者咽反射消失与床边吞咽评估(BSA)的诊断价值,并评估其与预后的关系。对242例急性卒中患者进行了咽反射测试和BSA。记录需要插入鼻胃管或胃造瘘管的患者数量,以及他们的出院目的地、出院时的巴氏指数和死亡率。受试者的平均年龄为76.5±10.2岁;37.6%为男性;41.7%的患者在BSA中存在吞咽困难;18.2%的患者咽反射消失。咽反射消失的患者中88.6%存在吞咽困难,咽反射正常的患者中31.3%存在吞咽困难。吞咽困难患者中38.6%咽反射消失,非吞咽困难患者中3.5%咽反射消失。将咽反射消失与BSA标准进行比较,其特异性为0.96,敏感性为0.39,阳性预测值为0.89,阴性预测值为0.69。回归分析发现,咽反射正常对于胃造瘘喂养的优势比[CI]为0.23[0.06 - 0.91],但不能预测其他预后。我们得出结论,在检测急性卒中患者的吞咽困难方面,咽反射与BSA具有相同的特异性,但敏感性低于BSA。咽反射正常可能对预防长期吞咽问题和肠内喂养需求具有保护作用。