Weyandt G
Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie der Julius-Maximilians-Universität Würzburg.
Hautarzt. 2005 Nov;56(11):1033-9. doi: 10.1007/s00105-005-1032-4.
The pathogenesis of acne inversa is follicular hyperkeratosis with occlusion and rupture. The subsequent acute inflammatory response leads to erythema, abscesses, fistulas, sinus tracts and scarring. Sites of predilection are the intertriginous regions. Many conservative therapies have only a supportive character. Therapy of choice is the early surgical intervention with complete excision of the involved areas, as conservative therapy is at best supportive. Although healing by second intention is preferred, all variations of flaps and grafts have been used. Usually the course of acne inversa lasts years until patients elect surgery after a physical and psychological odyssey.
化脓性汗腺炎的发病机制是毛囊角化过度伴堵塞和破裂。随后的急性炎症反应会导致红斑、脓肿、瘘管、窦道和瘢痕形成。好发部位是皮肤褶皱处。许多保守治疗仅具有辅助作用。首选的治疗方法是早期手术干预,彻底切除受累区域,因为保守治疗充其量只是辅助性的。尽管二期愈合是首选,但也使用了各种皮瓣和移植方法。通常,化脓性汗腺炎的病程会持续数年,直到患者在经历了身体和心理上的波折后选择手术治疗。