Rókusz László, László Liptay
First Department of Medicine, Central Military Hospital of the Hungarian Defense Forces, 1553 P.f. 1, Budapest, Hungary.
Mil Med. 2005 Aug;170(8):653-7. doi: 10.7205/milmed.170.8.653.
Sixty-one febrile episodes among 27 neutropenic patients with malignant hematological diseases were studied during a study period between 1998 and 2001. The results were compared with the previous 3-year period. The main differences in treatment were that we did not use ciprofloxacin prophylaxis routinely and we added granulocyte-macrophage colony-stimulating factor to the antimicrobial treatment regimen. The clinical and microbiological spectra of diseases shifted toward Gram-positive bacteremia and lower respiratory infections. The number and rate of infections and the mortality rate did not change significantly.
在1998年至2001年的研究期间，对27例患有恶性血液病的中性粒细胞减少患者的61次发热发作进行了研究。将结果与前三年进行了比较。治疗的主要差异在于我们没有常规使用环丙沙星进行预防，并且在抗菌治疗方案中添加了粒细胞-巨噬细胞集落刺激因子。疾病的临床和微生物谱向革兰氏阳性菌血症和下呼吸道感染转移。感染的数量和发生率以及死亡率没有显著变化。
