病理性打哈欠作为两名脑干缺血患者的首发症状。
Pathological yawning as a presenting symptom of brain stem ischaemia in two patients.
作者信息
Cattaneo L, Cucurachi L, Chierici E, Pavesi G
机构信息
Sezione di Neurologia, Dipartimento di Neuroscienze, Università degli Studi di Parma, Parma, Italy.
出版信息
J Neurol Neurosurg Psychiatry. 2006 Jan;77(1):98-100. doi: 10.1136/jnnp.2005.075267. Epub 2005 Sep 20.
Abstract
Two cases of brain stem stroke involving the upper pons and the ponto-mesencephalic junction presented with transient excessive pathological yawning, associated with gait ataxia and in one subject with upper limb and facial hemiparesis. A causal relation is hypothesised between the brain stem lesion and pathological yawning, possibly related to denervation hypersensitivity of a putative brain stem yawn centre. Excessive yawning may herald brain stem ischaemia.
摘要
两例累及脑桥上段和脑桥中脑交界处的脑干卒中患者出现短暂性过度病理性打哈欠，伴有步态共济失调，其中一例还伴有上肢和面部偏瘫。推测脑干病变与病理性打哈欠之间存在因果关系，可能与假定的脑干哈欠中枢的去神经超敏反应有关。过度打哈欠可能预示着脑干缺血。
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本文引用的文献
1
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Neurology. 2005 Apr 12;64(7):1227-32. doi: 10.1212/01.WNL.0000156520.46056.6B.
2
Contagious yawning and the brain.传染性哈欠与大脑。
Brain Res Cogn Brain Res. 2005 May;23(2-3):448-52. doi: 10.1016/j.cogbrainres.2004.11.011. Epub 2005 Jan 26.
3
Lesional location of lateral medullary infarction presenting hiccups (singultus).表现为呃逆（膈肌痉挛）的延髓外侧梗死的病灶部位
J Neurol Neurosurg Psychiatry. 2005 Jan;76(1):95-8. doi: 10.1136/jnnp.2004.039362.
4
Yawning despite trismus in a patient with locked-in syndrome caused by a thrombosed megadolichobasilar artery.一名因巨大基底动脉血栓形成导致闭锁综合征的患者，牙关紧闭时仍打哈欠。
Clin Neurol Neurosurg. 2003 Dec;106(1):44-6. doi: 10.1016/s0303-8467(03)00045-3.
5
Yawning.打哈欠。
J Neurol Neurosurg Psychiatry. 1958 Aug;21(3):203-9. doi: 10.1136/jnnp.21.3.203.
6
Yawning.
Sleep Med Rev. 2001 Aug;5(4):299-312. doi: 10.1053/smrv.2001.0175.
7
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J Neurol. 2002 Dec;249(12):1659-70. doi: 10.1007/s00415-002-0879-x.
8
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Neurology. 2000 Nov 28;55(10):1592-3. doi: 10.1212/wnl.55.10.1592.
9
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J Neurol. 1996 Mar;243(3):300-1. doi: 10.1007/BF00868532.
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