Yenice Ozlem, Temel Ahmet, Incili Burçin, Tuncer Neşe
Department of Ophthalmology, Marmara University School of Medicine, Istanbul, Turkey.
Graefes Arch Clin Exp Ophthalmol. 2006 May;244(5):589-95. doi: 10.1007/s00417-005-0083-7. Epub 2005 Sep 21.
The aim was to investigate short-wavelength sensitivity deficits in patients with migraine.
Fifteen migraine and 18 age-matched healthy volunteers with normal ophthalmologic examination participated in this study. Migraine characteristics were graded by the Migraine Disability Assessment Questionnaire (MIDAS). All participants underwent SWAP (short wavelength amplitude perimetry) testing using a Humphrey field analyzer; there was a 30-2 presentation pattern.
Short wavelength amplitude perimetry parameters for mean deviation (MD; p<0.0001) and pattern standard deviation (PSD; p<0.0001) were significantly worse in the migraine group. In the migraine group 53.3%. of eyes had glaucoma hemi-field tests (GHT) outside normal limits and 10 of these had early glaucomatous visual field loss. Statistically significant correlations were found between frequency of migraine attacks and MD (p=0.02; r=0.56) and PSD (p=0.03; r=0.41) and also between the MIDAS score and MD (p=0.03; r=0.49) and PSD (p=0.04; r=0.51). In all migraine cases with early glaucomatous visual field defect a corresponding site of the head was predominantly involved in headache (p=0.03).
Some patients with severe migraine have earlier defects on SWAP suggesting a common vascular insult of glaucoma and migraine, and all migraine cases with high MIDAS scores should be further evaluated for early glaucomatous visual field defects using SWAP.
目的是研究偏头痛患者的短波长敏感性缺陷。
15名偏头痛患者和18名年龄匹配、眼科检查正常的健康志愿者参与了本研究。偏头痛特征通过偏头痛残疾评估问卷（MIDAS）进行分级。所有参与者使用Humphrey视野分析仪进行SWAP（短波长振幅视野检查）测试；采用30-2呈现模式。
偏头痛组的平均偏差（MD；p<0.0001）和模式标准偏差（PSD；p<0.0001）的短波长振幅视野检查参数明显更差。在偏头痛组中，53.3%的眼睛青光眼半视野测试（GHT）超出正常范围，其中10只眼睛有早期青光眼性视野缺损。发现偏头痛发作频率与MD（p=0.02；r=0.56）和PSD（p=0.03；r=0.41）之间以及MIDAS评分与MD（p=0.03；r=0.
