Nakamura Toru, Kimura Taizo, Umehara Yasuhiko, Suzuki Kenji, Okamoto Kazuya, Okumura Takuya, Morizumi Sei, Kawabata Toshiki, Komiyama Akira
Division of Surgery, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Hamamatsu, Shizuoka, 430-8558, Japan.
Surg Today. 2005;35(10):890-2. doi: 10.1007/s00595-005-3022-7.
Hepatocellular carcinoma (HCC) is often treated most effectively by resection. Although improved surgical procedures and perioperative care have made hepatic resection safe, the prognosis of patients with HCC is still poor because of the high incidence of postoperative recurrence. The most common site of extrahepatic recurrence is the lung. However, because of its multiplicity and concurrent recurrence in the liver remnant, resection of pulmonary metastases form HCC is rarely beneficial. We report two cases of long-term survival after repeated pulmonary resection of metastasis from HCC. At the time of this report the two patients were free of disease, 110 months and 107 months, respectively, after their initial hepatectomy. These case reports show that pulmonary metastases from HCC can be successfully resected in selected patients.
肝细胞癌（HCC）通常通过切除治疗最为有效。尽管改进的手术方法和围手术期护理已使肝切除变得安全，但由于术后复发率高，HCC患者的预后仍然很差。肝外复发最常见的部位是肺。然而，由于肺转移灶的多发性以及肝残余组织中的并发复发，HCC肺转移灶的切除很少有益。我们报告了两例经反复肺切除治疗HCC转移灶后长期生存的病例。在撰写本报告时，这两名患者分别在初次肝切除术后110个月和107个月无疾病复发。这些病例报告表明，在选定的患者中，HCC肺转移灶可以成功切除。
