来源于总状升麻的三萜糖苷。

Triterpenoid glycoside from Cimicifuga racemosa.

作者信息

Lai G F, Wang Y-F, Fan L-M, Cao J-X, Luo S-D

机构信息

State Key Laboratory of Phytochemistry and Plant Resource in West China, Yunnan, China.

出版信息

J Asian Nat Prod Res. 2005 Oct;7(5):695-9. doi: 10.1080/1028602042000324817.

DOI:10.1080/1028602042000324817

PMID:16176901

Abstract

One new triterpene glycoside, cimiracemoside , and 14 known triterpene glycosides have been isolated from the rhizome extracts of black cohosh (Cimicifuga racemosa). On the basis of spectral and chemical evidence, the structure of the new compound was elucidated to be 12beta-acetoxycimigenol-3-O-beta-D-xylopranoside, and the known compounds were identified to be 25-acetylcimigenol xyloside, cimigenol-3-O-beta-D-xylopyranoside, acetin, 27-deoxyacetin, cimicifugoside H-1, 23-O-acetylshengmanol 3-O-beta-D-xylopranoside, foetidinol-3-O-beta-xyloside, cimicifugoside H-2, 25-O-methylcimigenol xyloside, 21-hydroxycimigenol-3-O-beta-D-xylopyranoside, 24-epi-7,8-didehydrocimigenol-3-xyloside, cimidahurinine, cimidahurine and cimifugin. The compounds, , and showed weak antibacterial activities in the agar diffusion assay.

摘要

从黑升麻（毛茛科升麻属植物）根茎提取物中分离出一种新的三萜糖苷——升麻糖苷，以及14种已知的三萜糖苷。基于光谱和化学证据，确定新化合物的结构为12β - 乙酰氧基升麻醇 - 3 - O - β - D - 木糖苷，已知化合物分别鉴定为25 - 乙酰基升麻醇木糖苷、升麻醇 - 3 - O - β - D - 木糖苷、乙酰丁香酮、27 - 脱氧乙酰丁香酮、升麻糖苷H - 1、23 - O - 乙酰升麻醇3 - O - β - D - 木糖苷、升麻素醇 - 3 - O - β - 木糖苷、升麻糖苷H - 2、25 - O - 甲基升麻醇木糖苷、21 - 羟基升麻醇 - 3 - O - β - D - 木糖苷、24 - 表 - 7,8 - 二脱氢升麻醇 - 3 - 木糖苷、升麻达里宁、升麻达里宁和升麻苷。在琼脂扩散试验中，化合物、和表现出较弱的抗菌活性。