Spellacy W N, Tsibris J C, Hunter-Bonner D L, Smalling S, Chez R A, Angel J L, O'Brien W F
Department of Obstetrics and Gynecology, University of South Florida, College of Medicine, Tampa 33606.
Contraception. 1992 Jun;45(6):533-9. doi: 10.1016/0010-7824(92)90104-2.
Twenty-five women had their carbohydrate metabolism prospectively evaluated during the six months that they used a gestodene and ethinyl estradiol monophasic oral contraceptive. Serum glucose and insulin levels were measured during a 75-gram three-hour oral glucose tolerance test. At the six-month test, the three-hour glucose and the fasting and three-hour insulin values were significantly elevated. The literature on carbohydrate metabolism during gestodene oral contraceptive use is also reviewed.
