Hu J F
Harbin Medical University, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Zhong Liu Za Zhi. 1992 Mar;14(2):119-22.
As a practical application of theory, the susceptible exposure age and latency distribution of consumption of alcohol and tobacco in relation to stomach cancer is discussed. It was revealed that, in univariate, estimation of the susceptible exposure age of alcohol and tobacco were 15-50 years and 35-50 years. The estimated latency were 35 years and 15 years. Those of accumulative period and preneoplastic period were 30 and 10 years. In a multivariate analysis, the latency for alcohol consumption was changed to 20 years as the incubation time in preneoplastic period was prolonged by 5 years due to consumption of vegetables. This could give a theoretical interpretation of second line cancer prevention.
作为理论的实际应用，本文讨论了饮酒和吸烟与胃癌相关的易感暴露年龄和潜伏期分布。结果显示，单因素分析中，酒精和烟草的易感暴露年龄估计分别为15 - 50岁和35 - 50岁。估计潜伏期分别为35年和15年。累积期和癌前期的潜伏期分别为30年和10年。多因素分析中，由于蔬菜摄入使癌前期的潜伏期延长5年，饮酒的潜伏期变为20年。这可为二线癌症预防提供理论解释。
