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贝利婴儿神经发育筛查工具在早产儿中的应用。

Use of the bayley infant neurodevelopmental screener with premature infants.

作者信息

Gücüyener Kivilcim, Ergenekon Ebru, Soysal A Sebnem, Aktaş Anil, Derinöz Okşan, Koç E, Atalay Y

机构信息

Departments of Pediatric Neurology, Medical Faculty, Gazi University, Besevler, Ankara, Turkey.

出版信息

Brain Dev. 2006 Mar;28(2):104-8. doi: 10.1016/j.braindev.2005.05.006. Epub 2005 Sep 21.

DOI:10.1016/j.braindev.2005.05.006
PMID:16181756
Abstract

OBJECTIVE

To examine the utility of the Bayley Infant Neurodevelopmental Screener (BINS) for the neurodevelopmental follow up of high-risk preterms.

METHODS

The study group consisted of 122 preterm infants of the gestational ages between 26 and 37 weeks. Medical factors such as; mean birth weight, gestational age, gender, birth place and type, number of multiple pregnancy, days of hospitalization and oxygen therapy, use of antenatal steroids, and occurrence of sepsis for each patient were evaluated. The neurodevelopmental examination and BINS administration was made at each visit to the patients whose ages were adjusted for prematurity.

RESULTS

At the corrected age of 7-10 months patients at 26-29 GA had significantly lower total means of BINS scores when compared to those of the other two groups at 30-32 and 33-37 GA (P<0.01 and P<0.001). At the corrected age of 3-4 months, the total means of the BINS scores of the patients at 30-32 GA were lower than that of the patients at 33-37 GA (P<0.009). at 7-10 months the scores of the items defining the expressive and cognitive functions of the patients at 26-29 GA were lower than those of the patients at 30-32 GA (P<0.05) and 33-37 GA (P<0.05). At 16-20 months the mean scores of the items of expressive functions were significantly lower in patients of the 26-29 GA compared to those of the patients of 33-37 GA (P<0.03).

CONCLUSION

As data accumulates, BINS will turn out to be a quick way of determining infants at risk of developmental delay in many aspects of neurologically high risk conditions.

摘要

目的

探讨贝利婴儿神经发育筛查量表(BINS)在高危早产儿神经发育随访中的应用价值。

方法

研究组由122例孕周在26至37周之间的早产儿组成。评估了每位患者的医学因素,如平均出生体重、孕周、性别、出生地点和类型、多胎妊娠数、住院天数和氧疗情况、产前类固醇的使用以及败血症的发生情况。对年龄进行早产校正的患者每次就诊时均进行神经发育检查并使用BINS进行评估。

结果

在矫正年龄7至10个月时,26至29孕周的患者BINS总分均值显著低于30至32孕周和33至37孕周的其他两组患者(P<0.01和P<0.001)。在矫正年龄3至4个月时,30至32孕周患者的BINS总分均值低于33至37孕周的患者(P<0.009)。在7至10个月时,26至29孕周患者定义表达和认知功能的项目得分低于30至32孕周(P<0.05)和33至37孕周(P<0.05)的患者。在16至20个月时,26至29孕周患者表达功能项目的平均得分显著低于33至37孕周的患者(P<0.03)。

结论

随着数据的积累,BINS将成为在神经高危状况的许多方面快速确定有发育迟缓风险婴儿的方法。

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