Azevedo L S, Castro M C R, Monteiro de Carvalho D B, d'Avila D O, Contieri F, Gonçalves R T, Manfro R, Ianhez L E
Hospital das Clinicas da Faculdade de Medicina da USP.
Transplant Proc. 2005 Jul-Aug;37(6):2746-7. doi: 10.1016/j.transproceed.2005.05.005.
To evaluate the frequency of delayed graft function (DGF) in kidney transplant centers in Brazil, we sent a questionnaire requesting information on the number of cadaveric donor kidney transplants performed during the years 2000, 2001, and 2002, the number of early nonfunctioning grafts, and the number of patients on dialysis during the first posttransplant week with subsequent recovery. Among all centers performing more than 50 kidney transplants during the last year of evaluation, 6, performing 612 cadaveric kidney transplants during the study period, replied to the questionnaire. Sixty procedures (9.7%) resulted in nonfunctioning grafts, while 312 (55.6%) patients required dialysis during the first Ptx week: 216 (53.9%) in 2000, 189 (62.3%) in 2001, and 216 (51.6%) in 2002. The frequency of DGF during the study period was higher than that noted by several previous foreign studies. To better evaluate the possible causes of this finding, a more extensive and focused study is warranted.
为评估巴西肾脏移植中心延迟移植肾功能(DGF)的发生率,我们发放了一份问卷,询问2000年、2001年和2002年进行的尸体供肾移植数量、早期无功能移植物数量以及移植后第一周内接受透析且随后恢复的患者数量。在评估的最后一年中进行了超过50例肾脏移植的所有中心中,有6个中心(在研究期间进行了612例尸体肾移植)回复了问卷。60例手术(9.7%)导致移植物无功能,而312例(55.6%)患者在移植后第一周需要透析:2000年为216例(53.9%),2001年为189例(62.3%),2002年为216例(51.6%)。研究期间DGF的发生率高于此前一些国外研究报道的发生率。为更好地评估这一发现的可能原因,有必要进行更广泛、更有针对性的研究。